product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Integrin ▀4/CD104 Antibody
catalog :
MAB4060
quantity :
100 ug (also 25 ug)
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
422325
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 12
Reference
Pontiggia L, Ahuja A, Yosef H, R xfc tsche D, Reichmann E, Moehrlen U, et al. Human Basal and Suprabasal Keratinocytes Are Both Able to Generate and Maintain Dermo-Epidermal Skin Substitutes in Long-Term In Vivo Experiments. Cells. 2022;11: pubmed publisher
Beauvais D, Nelson S, Adams K, Stueven N, Jung O, Rapraeger A. Plasma membrane proteoglycans syndecan-2 and syndecan-4 engage with EGFR and RON kinase to sustain carcinoma cell cycle progression. J Biol Chem. 2022;298:102029 pubmed publisher
Hara T, Kasagi Y, Wang J, Sasaki M, Aaron B, Karami A, et al. CD73+ Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis. Cell Mol Gastroenterol Hepatol. 2022;13:1449-1467 pubmed publisher
Keller C, Hu Y, Ruud K, VanDeen A, Martinez S, Kahn B, et al. Human Breast Extracellular Matrix Microstructures and Protein Hydrogel 3D Cultures of Mammary Epithelial Cells. Cancers (Basel). 2021;13: pubmed publisher
Yang Y, Wang Y, Che X, Hou K, Wu J, Zheng C, et al. Integrin α5 promotes migration and invasion through the FAK/STAT3/AKT signaling pathway in icotinib-resistant non-small cell lung cancer cells. Oncol Lett. 2021;22:556 pubmed publisher
Giampieri R, Piva F, Occhipinti G, Bittoni A, Righetti A, Pagliaretta S, et al. Clinical impact of different exosomes' protein expression in pancreatic ductal carcinoma patients treated with standard first line palliative chemotherapy. PLoS ONE. 2019;14:e0215990 pubmed publisher
Rijal G, Wang J, Yu I, Gang D, Chen R, Li W. Porcine Breast Extracellular Matrix Hydrogel for Spatial Tissue Culture. Int J Mol Sci. 2018;19: pubmed publisher
Rajan A, Persson B, Frängsmyr L, Olofsson A, Sandblad L, Heino J, et al. Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells. Sci Rep. 2018;8:10019 pubmed publisher
Russo V, Klein T, Lim D, Solis N, Machado Y, Hiroyasu S, et al. Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction. Sci Rep. 2018;8:9690 pubmed publisher
Storm R, Persson B, Skalman L, Frängsmyr L, Lindström M, Rankin G, et al. Human Adenovirus Type 37 Uses αVβ1 and α3β1 Integrins for Infection of Human Corneal Cells. J Virol. 2017;91: pubmed publisher
Li X, Rossen N, Sinn P, Hornick A, Steines B, Karp P, et al. Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease. PLoS ONE. 2013;8:e83624 pubmed publisher
Mierke C, Frey B, Fellner M, Herrmann M, Fabry B. Integrin ?5?1 facilitates cancer cell invasion through enhanced contractile forces. J Cell Sci. 2011;124:369-83 pubmed publisher
product information
master code :
MAB4060
SKU :
MAB4060
product name :
Human Integrin ▀4/CD104 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Integrin ß4/CD104 Antibody from R&D Systems is a mouse monoclonal antibody to Integrin beta 4/CD104. This antibody reacts with human. The Human Integrin ß4/CD104 Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Western Blot,Neutralization,ELISA Detection,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready.
target :
Integrin beta 4/CD104
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
422325
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant human Integrin ▀4/CD104, Asn28-Ser710, Accession # P16144
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Integrin ▀4/CD104 in Western blots. In Western blots, no cross-reactivity with recombinant human Integrin ▀1, ▀2, ▀3, ▀5, ▀6, ▀8, or recombinant mouse Integrin ▀4 is observed.
gene symbol :
ITGB4
top caption :
Integrin ss4/CD104 antibody in A431 Human Cell Line by Immunocytochemistry (ICC).
accessionNumbers :
P16144
applications :
Flow Cytometry,Immunoprecipitation,Western Blot,Neutralization,ELISA Detection,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready
USD :
439 USD
alt names :
CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4, ITGB4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.