Human/Mouse IL-5 Antibody | R&D Systems MAB405 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse IL-5 Antibody

catalog :

MAB405

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

TRFK5

reactivity :

human, mouse

application :

neutralization

citations: 16

Reference
D Souza S, Shen X, Fung I, Ye L, Kuentzel M, Chittur S, et al. Compartmentalized effects of aging on group 2 innate lymphoid cell development and function. Aging Cell. 2019;18:e13019 pubmed publisher
Mantani P, Dunér P, Bengtsson E, Ljungcrantz I, Sundius L, To F, et al. Interleukin-25 (IL-25) has a protective role in atherosclerosis development in the aortic arch in mice. J Biol Chem. 2018;293:6791-6801 pubmed publisher
Petersen C, Meyer A, De Salvo C, Choi E, Schlegel C, Petersen A, et al. A signalling cascade of IL-33 to IL-13 regulates metaplasia in the mouse stomach. Gut. 2017;: pubmed publisher
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58:169-77 pubmed publisher
Yamada T, Tani Y, Nakanishi H, Taguchi R, Arita M, Arai H. Eosinophils promote resolution of acute peritonitis by producing proresolving mediators in mice. FASEB J. 2011;25:561-8 pubmed publisher
Whelan C. Evidence that 13-14 di-hydro, 15-keto prostaglandin D(2)-induced airway eosinophilia in guinea-pigs is independent of interleukin-5. Inflamm Res. 2009;58:103-8 pubmed publisher
Qui H, Ferrell E, Nolan N, Phelps B, Tabibiazar R, Whitney D, et al. Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines. Clin Chem. 2007;53:2010-2 pubmed
Pfleger C, Schloot N, ter Veld F. Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays. J Immunol Methods. 2008;329:214-8 pubmed
Xavier Elsas P, Santos Maximiano E, Queto T, Mendonça Sales S, Joseph D, Gaspar Elsas M, et al. Ectopic lung transplantation induces the accumulation of eosinophil progenitors in the recipients' lungs through an allergen- and interleukin-5-dependent mechanism. Clin Exp Allergy. 2007;37:29-38 pubmed
Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck L, et al. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin Immunol. 2006;120:220-31 pubmed
Wen H, Hogaboam C, Gauldie J, Kunkel S. Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile. Am J Pathol. 2006;168:1940-50 pubmed
Nygaard U, Ormstad H, Aase A, Løvik M. The IgE adjuvant effect of particles: characterisation of the primary cellular response in the draining lymph node. Toxicology. 2005;206:181-93 pubmed
Couillin I, Maillet I, Vargaftig B, Jacobs M, Paesen G, Nuttall P, et al. Arthropod-derived histamine-binding protein prevents murine allergic asthma. J Immunol. 2004;173:3281-6 pubmed
Kobayashi T, Iijima K, Kita H. Marked airway eosinophilia prevents development of airway hyper-responsiveness during an allergic response in IL-5 transgenic mice. J Immunol. 2003;170:5756-63 pubmed
Tomaki M, Zhao L, Sjöstrand M, Linden A, Ichinose M, Lotvall J. Comparison of effects of anti-IL-3, IL-5 and GM-CSF treatments on eosinophilopoiesis and airway eosinophilia induced by allergen. Pulm Pharmacol Ther. 2002;15:161-8 pubmed
Lukacs N, Berlin A, Schols D, Skerlj R, Bridger G. AMD3100, a CxCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivity. Am J Pathol. 2002;160:1353-60 pubmed

product information

brand :

R&D Systems

master code :

MAB405

SKU :

MAB405-100

product name :

Human/Mouse IL-5 Antibody

description :

The Human/Mouse IL-5 Antibody from R&D Systems is a rat monoclonal antibody to IL-5. This antibody reacts with human, mouse. The Human/Mouse IL-5 Antibody has been validated for the following applications: Neutralization, Intracellular Staining by Flow Cytometry, CyTOF-reported, ELISA Capture (Matched Antibody Pair), ELISA Capture (Matched Antibody Pair).

target :

IL-5

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

TRFK5

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse T cell clone-derived partially purified recombinant mouse IL-5

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human, Mouse

specificity :

Detects human and mouse IL-5 in ELISAs. In sandwich immunoassays with BAM6051 as the detection antibody, no cross-reactivity with recombinant human (rh) IL-3, rhGM-CSF, or recombinant mouse (rm) IL-5 is observed. In sandwich ELISAs with BAM705 as the detection antibody, no cross-reactivity with rhIL-5, rmIL-3, or rmGM-CSF is observed.

gene symbol :

IL5

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB405

applications :

Neutralization, Intracellular Staining by Flow Cytometry, CyTOF-reported, ELISA Capture (Matched Antibody Pair), ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

359 USD

alt names :

BCDF mu, B-cell differentiation factor I, BCGFII, EDF, Eo-CSF, Eosinophil differentiation factor, IL5, IL-5T-cell replacing factor, interleukin 5 (colony-stimulating factor, eosinophil), interleukin-5, TRF, TRFB cell differentiation factor I

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.