Mouse IL-4 Antibody | R&D Systems MAB404 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IL-4 Antibody

catalog :

MAB404

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

30340

reactivity :

human, mouse

application :

western blot, ELISA, neutralization, blocking or activating experiments

citations: 21

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; mouse; loading ...; fig s5c	Weiss J, Chen W, Nyuydzefe M, Trzeciak A, Flynn R, Tonra J, et al. ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings. Sci Signal. 2016;9:ra73 pubmed publisher
blocking or activating experiments; mouse; fig 3b	Nata T, Basheer A, Cocchi F, van Besien R, Massoud R, Jacobson S, et al. Targeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member cytokines with selectable target spectrum. J Biol Chem. 2015;290:22338-51 pubmed publisher
	Yang J, Kalim K, Li Y, Zheng Y, Guo F. Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation. J Leukoc Biol. 2019;106:1139-1151 pubmed publisher
	Nam Y, Jung S, Rim Y, Jung H, Lee K, Park N, et al. Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis. PLoS ONE. 2018;13:e0198740 pubmed publisher
	Ramírez M, Santos S, Martínez O, Rodriguez R, Miranda E, Ramos Perez W, et al. Characterization of the immune response elicited by the vaccinia virus L3 protein delivered as naked DNA. Vaccine. 2018;36:2049-2055 pubmed publisher
	Hu Y, Lao L, Mao J, Jin W, Luo H, Charpentier T, et al. Armc5 deletion causes developmental defects and compromises T-cell immune responses. Nat Commun. 2017;8:13834 pubmed publisher
	Solt L, Banerjee S, Campbell S, Kamenecka T, Burris T. ROR inverse agonist suppresses insulitis and prevents hyperglycemia in a mouse model of type 1 diabetes. Endocrinology. 2015;156:869-81 pubmed publisher
	Reba S, Li Q, Onwuzulike S, Ding X, Karim A, Hernandez Y, et al. TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis. Eur J Immunol. 2014;44:1410-21 pubmed publisher
	Gomez M, Talke Y, Hofmann C, Ketelsen I, Hermann F, Reich B, et al. Basophils control T-cell responses and limit disease activity in experimental murine colitis. Mucosal Immunol. 2014;7:188-99 pubmed publisher
	Costa M, Bornstein V, Candéa A, Henriques Pons A, Henriques M, Penido C. CCL25 induces ???? integrin-dependent migration of IL-17? ?? T lymphocytes during an allergic reaction. Eur J Immunol. 2012;42:1250-60 pubmed publisher
	Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58:169-77 pubmed publisher
	Jin W, Qi S, Luo H. The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function. BMC Immunol. 2011;12:68 pubmed publisher
	Wieland C, van der Windt G, Florquin S, McKenzie A, van der Poll T. ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis. Microbes Infect. 2009;11:524-30 pubmed publisher
	McKinley L, Alcorn J, Peterson A, Dupont R, Kapadia S, Logar A, et al. TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J Immunol. 2008;181:4089-97 pubmed
	Mabalirajan U, Dinda A, Kumar S, Roshan R, Gupta P, Sharma S, et al. Mitochondrial structural changes and dysfunction are associated with experimental allergic asthma. J Immunol. 2008;181:3540-8 pubmed
	Ito H, Ando K, Ishikawa T, Nakayama T, Taniguchi M, Saito K, et al. Role of Valpha14+ NKT cells in the development of Hepatitis B virus-specific CTL: activation of Valpha14+ NKT cells promotes the breakage of CTL tolerance. Int Immunol. 2008;20:869-79 pubmed publisher
	Wieland C, van der Windt G, Wiersinga W, Florquin S, van der Poll T. CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis. Immunology. 2008;125:272-9 pubmed publisher
	Chiang Y, Chang C, Chang S, Yang W, Shyur L. Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator. J Ethnopharmacol. 2007;110:532-8 pubmed
	Wen H, Hogaboam C, Gauldie J, Kunkel S. Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile. Am J Pathol. 2006;168:1940-50 pubmed
	Bednarski J, Warner R, Rao T, Leonetti F, Yung R, Richardson B, et al. Attenuation of autoimmune disease in Fas-deficient mice by treatment with a cytotoxic benzodiazepine. Arthritis Rheum. 2003;48:757-66 pubmed
	Lukacs N, Berlin A, Schols D, Skerlj R, Bridger G. AMD3100, a CxCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivity. Am J Pathol. 2002;160:1353-60 pubmed

product information

brand :

R&D Systems

master code :

MAB404

SKU :

MAB404-100

product name :

Mouse IL-4 Antibody

description :

The Mouse IL-4 Antibody from R&D Systems is a rat monoclonal antibody to IL-4. This antibody reacts with mouse. The Mouse IL-4 Antibody has been validated for the following applications: Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

IL-4

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

30340

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse IL-4, His23-Ser140, Accession # P07750

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse IL-4 in ELISAs and Western blots.

gene symbol :

IL4

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB404

accessionNumbers :

P07750

applications :

Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

369 USD

alt names :

B cell growth factor 1, BCDF, B-cell stimulatory factor 1, BCGF1, BCGF-1, binetrakin, BSF1, BSF-1, IL4, IL-4B_cell stimulatory factor 1, IL4E12, interleukin 4, interleukin-4, Lymphocyte stimulatory factor 1, MGC79402, Pitrakinra

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.