Human/Mouse Myocardin Antibody | R&D Systems MAB4028 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse Myocardin Antibody

catalog :

MAB4028

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

355521

reactivity :

human, mouse, dogs

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 15

Reference
Paredes F, Williams H, Liu X, Holden C, Bogan B, Wang Y, et al. The mitochondrial protease ClpP is a druggable target that controls VSMC phenotype by a SIRT1-dependent mechanism. Redox Biol. 2024;73:103203 pubmed publisher
Tucker T, Tsukasaki Y, Sakai T, Mitsuhashi S, Komatsu S, Jeffers A, et al. Myocardin Is Involved in Mesothelial-Mesenchymal Transition of Human Pleural Mesothelial Cells. Am J Respir Cell Mol Biol. 2019;61:86-96 pubmed publisher
Dai J, Zhou Q, Chen J, Rexius Hall M, Rehman J, Zhou G. Alpha-enolase regulates the malignant phenotype of pulmonary artery smooth muscle cells via the AMPK-Akt pathway. Nat Commun. 2018;9:3850 pubmed publisher
Dai J, Zhou Q, Tang H, Chen T, Li J, Raychaudhuri P, et al. Smooth muscle cell-specific FoxM1 controls hypoxia-induced pulmonary hypertension. Cell Signal. 2018;51:119-129 pubmed publisher
Xi G, Wai C, White M, Clemmons D. Down-regulation of Insulin Receptor Substrate 1 during Hyperglycemia Induces Vascular Smooth Muscle Cell Dedifferentiation. J Biol Chem. 2017;292:2009-2020 pubmed publisher
Chen T, Zhou Q, Tang H, Bozkanat M, Yuan J, Raj J, et al. miR-17/20 Controls Prolyl Hydroxylase 2 (PHD2)/Hypoxia-Inducible Factor 1 (HIF1) to Regulate Pulmonary Artery Smooth Muscle Cell Proliferation. J Am Heart Assoc. 2016;5: pubmed
Cushing L, Costinean S, Xu W, Jiang Z, Madden L, Kuang P, et al. Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature. PLoS Genet. 2015;11:e1005238 pubmed publisher
Madonna R, Geng Y, Bolli R, Rokosh G, Ferdinandy P, Patterson C, et al. Co-activation of nuclear factor-?B and myocardin/serum response factor conveys the hypertrophy signal of high insulin levels in cardiac myoblasts. J Biol Chem. 2014;289:19585-98 pubmed publisher
Yao Y, Chen Z, Norris E, Strickland S. Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity. Nat Commun. 2014;5:3413 pubmed publisher
Abdalla M, Goc A, Segar L, Somanath P. Akt1 mediates ?-smooth muscle actin expression and myofibroblast differentiation via myocardin and serum response factor. J Biol Chem. 2013;288:33483-93 pubmed publisher
Madonna R, Taylor D, Geng Y, De Caterina R, Shelat H, Perin E, et al. Transplantation of mesenchymal cells rejuvenated by the overexpression of telomerase and myocardin promotes revascularization and tissue repair in a murine model of hindlimb ischemia. Circ Res. 2013;113:902-14 pubmed publisher
Lu T, Lim K, Molostvov G, Yang Y, Yiao S, Zehnder D, et al. Induction of intracellular heat-shock protein 72 prevents the development of vascular smooth muscle cell calcification. Cardiovasc Res. 2012;96:524-32 pubmed publisher
Pfisterer L, Feldner A, Hecker M, Korff T. Hypertension impairs myocardin function: a novel mechanism facilitating arterial remodelling. Cardiovasc Res. 2012;96:120-9 pubmed publisher
Lim K, Lu T, Molostvov G, Lee C, Lam F, Zehnder D, et al. Vascular Klotho deficiency potentiates the development of human artery calcification and mediates resistance to fibroblast growth factor 23. Circulation. 2012;125:2243-55 pubmed publisher
Davis Dusenbery B, Chan M, Reno K, Weisman A, Layne M, Lagna G, et al. down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4. J Biol Chem. 2011;286:28097-110 pubmed publisher

product information

master code :

MAB4028

SKU :

MAB4028

product name :

Human/Mouse Myocardin Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse Myocardin Antibody from R&D Systems is a mouse monoclonal antibody to Myocardin. This antibody reacts with canine,human,mouse,transgenic mouse. The Human/Mouse Myocardin Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin.

target :

Myocardin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

355521

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human Myocardin, Met97-Leu290, Accession # Q8IZQ8

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Canine,Human,Mouse,Transgenic Mouse

specificity :

Detects human and mouse Myocardin in Western blots.

gene symbol :

MYOCD

top caption :

Detection of Human Myocardin antibody by Western Blot.

accessionNumbers :

Q8IZQ8

applications :

Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin

USD :

469 USD

alt names :

BSAC2A, MYCD, myocardin, MYOCD, Srfcp

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage