Mouse IL-1▀/IL-1F2 Antibody | R&D Systems MAB4012 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IL-1▀/IL-1F2 Antibody

catalog :

MAB4012

quantity :

100 ug (also 25 ug)

price :

459 USD

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

B122

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, neutralization, immunoprecipitation, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 13

Reference
Han X, Ning Y, Dou X, Wang Y, Shan Q, Shi K, et al. Cornus officinalis with high pressure wine steaming enhanced anti-hepatic fibrosis: Possible through SIRT3-AMPK axis. J Pharm Anal. 2024;14:100927 pubmed publisher
Yoshida T, Das N, Carpenter A, Izadpanah R, Kumar S, Gautam S, et al. Minocycline reverses IL-17A/TRAF3IP2-mediated p38 MAPK/NF-κB/iNOS/NO-dependent cardiomyocyte contractile depression and death. Cell Signal. 2020;73:109690 pubmed publisher
McKnight Q, Jenkins S, Li X, Nelson T, Marlier A, Cantley L, et al. IL-1β Drives Production of FGF-23 at the Onset of Chronic Kidney Disease in Mice. J Bone Miner Res. 2020;35:1352-1362 pubmed publisher
Hackett E, Charles Messance H, O Leary S, Gleeson L, Muñoz Wolf N, Case S, et al. Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21. Cell Rep. 2020;30:124-136.e4 pubmed publisher
Zhou H, Slominski R, Seymour L, Bell M, Dave P, Atumonye J, et al. Ex vivo culture of mouse skin activates an interleukin 1 alpha-dependent inflammatory response. Exp Dermatol. 2020;29:102-106 pubmed publisher
Udjus C, Cero F, Halvorsen B, Behmen D, Carlson C, Bendiksen B, et al. Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2019;316:L999-L1012 pubmed publisher
Kong Y, Li G, Zhang W, Hua X, Zhou C, Xu T, et al. Nicotinamide phosphoribosyltransferase aggravates inflammation and promotes atherosclerosis in ApoE knockout mice. Acta Pharmacol Sin. 2019;: pubmed publisher
Li C, Zhang Y, Cheng X, Yuan H, Zhu S, Liu J, et al. PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism. Dev Cell. 2018;46:441-455.e8 pubmed publisher
Li D, Fu H, Tong J, Li Y, Qu L, Wang P, et al. Cholinergic anti-inflammatory pathway inhibits neointimal hyperplasia by suppressing inflammation and oxidative stress. Redox Biol. 2018;15:22-33 pubmed publisher
Maler M, Nielsen P, Stichling N, Cohen I, Ruzsics Z, Wood C, et al. Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages. MBio. 2017;8: pubmed publisher
Botelho F, Nikota J, Bauer C, Morissette M, Iwakura Y, Kolbeck R, et al. Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1?-dependent in mice. Respir Res. 2012;13:81 pubmed publisher
Botelho F, Bauer C, Finch D, Nikota J, Zavitz C, Kelly A, et al. IL-1?/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice. PLoS ONE. 2011;6:e28457 pubmed publisher
Rider P, Carmi Y, Guttman O, Braiman A, Cohen I, Voronov E, et al. IL-1? and IL-1? recruit different myeloid cells and promote different stages of sterile inflammation. J Immunol. 2011;187:4835-43 pubmed publisher

product information

master code :

MAB4012

SKU :

MAB4012

product name :

Mouse IL-1▀/IL-1F2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse IL-1ß/IL-1F2 Antibody from R&D Systems is a hamster monoclonal antibody to IL-1 beta/IL-1F2. This antibody reacts with mouse,rat. The Mouse IL-1ß/IL-1F2 Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,In vivo assay,Immunoprecipitation.

target :

IL-1 beta/IL-1F2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

B122

concentration :

LYOPH

conjugate :

Unconjugated

host :

Hamster

immunogen :

E. coli -derived recombinant mouse IL-1▀, Accession # P10749

isotype :

IgG

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse,Rat

specificity :

Detects mouse IL-1▀/IL-1 F2 in direct ELISAs and Western blots. In Western blots, shows 100% cross-reactivity with recombinant rat (rr) IL-1▀ and rcrIL-1▀, 15%-35 % with rhIL-1▀ and rpIL-1▀, and no cross-reactivity with rmIL-1 alpha , rmIL-18, or rhIL-1▀rp.

gene symbol :

IL1B

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by IL-1ss/IL-1F2 and Neutralization by Mouse IL-1ss/IL-1F2 Antibody.

accessionNumbers :

P10749

applications :

Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,In vivo assay,Immunoprecipitation

USD :

459 USD

alt names :

catabolin, IL-1, IL1 beta, IL-1 beta, IL-1b, IL1B, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin 1, beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage