Mouse IL-1 alpha /IL-1F1 Antibody | R&D Systems MAB4001 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IL-1 alpha /IL-1F1 Antibody

catalog :

MAB4001

quantity :

500 ug (also 25 ug)

price :

559 USD

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

ALF161

reactivity :

mouse

application :

western blot, neutralization, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 5

Reference
Mello A, Ngodup T, Lee Y, Donahue K, Li J, Rao A, et al. Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer. Oncogenesis. 2022;11:56 pubmed publisher
Zhou H, Slominski R, Seymour L, Bell M, Dave P, Atumonye J, et al. Ex vivo culture of mouse skin activates an interleukin 1 alpha-dependent inflammatory response. Exp Dermatol. 2020;29:102-106 pubmed publisher
Biffi G, Oni T, Spielman B, Hao Y, Elyada E, Park Y, et al. IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2019;9:282-301 pubmed publisher
Botelho F, Nikota J, Bauer C, Morissette M, Iwakura Y, Kolbeck R, et al. Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1?-dependent in mice. Respir Res. 2012;13:81 pubmed publisher
Botelho F, Bauer C, Finch D, Nikota J, Zavitz C, Kelly A, et al. IL-1?/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice. PLoS ONE. 2011;6:e28457 pubmed publisher

product information

master code :

MAB4001

SKU :

MAB4001

product name :

Mouse IL-1 alpha /IL-1F1 Antibody

unit size :

500 ug (also 25 ug)

description :

The Mouse IL-1 alpha /IL-1F1 Antibody from R&D Systems is a hamster monoclonal antibody to IL-1 alpha/IL-1F1. This antibody reacts with mouse. The Mouse IL-1 alpha /IL-1F1 Antibody has been validated for the following applications: Neutralization,In vivo assay,Immunoprecipitation,Western Blot.

target :

IL-1 alpha/IL-1F1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

ALF161

conjugate :

Unconjugated

host :

Hamster

immunogen :

E. coli -derived recombinant mouse IL-1 alpha

isotype :

IgG

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse IL-1 alpha in direct ELISAs and Western blots. In direct ELISAs, 100% and 30% cross-reactivity was observed with cotton rat IL-1 alpha and rat IL-1 alpha , respectively, and no cross-reactivity with recombinant human (rh) IL-1 alpha , rpIL-1 alpha , rmIL-1▀, or rmIL-18 was observed.

gene symbol :

IL1A

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by IL-1a/IL-1F1 and Neutralization by Mouse IL-1a/IL-1F1 Antibody.

applications :

Neutralization,In vivo assay,Immunoprecipitation,Western Blot

USD :

559 USD

alt names :

BAF, Hematopoietin-1, IL1, IL1 alpha, IL-1 alpha, IL1A, IL-1A, IL1-ALPHA, IL1F1, IL-1F1, IL1F1hematopoietin-1, interleukin 1, alpha, interleukin-1 alpha, LAF, LEM, preinterleukin 1 alpha, pro-interleukin-1-alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage