product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse IL-1 alpha /IL-1F1 Antibody
catalog :
MAB400-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
479 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
40508
reactivity :
human, mouse
application :
ELISA, neutralization
more info or order :
R&D Systems product webpage
citations: 8
Reference
Polykratis A, Martens A, Eren R, Shirasaki Y, Yamagishi M, Yamaguchi Y, et al. A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain. Nat Cell Biol. 2019;21:731-742 pubmed publisher
Shiraishi M, Shintani Y, Shintani Y, Ishida H, Saba R, Yamaguchi A, et al. Alternatively activated macrophages determine repair of the infarcted adult murine heart. J Clin Invest. 2016;126:2151-66 pubmed publisher
Dankbar B, Fennen M, Brunert D, Hayer S, Frank S, Wehmeyer C, et al. Myostatin is a direct regulator of osteoclast differentiation and its inhibition reduces inflammatory joint destruction in mice. Nat Med. 2015;21:1085-90 pubmed publisher
Fu X, Xiao J, Wei Y, Li S, Liu Y, Yin J, et al. Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion. Cell Res. 2015;25:655-73 pubmed publisher
Taniguchi K, Arima K, Masuoka M, Ohta S, Shiraishi H, Ontsuka K, et al. Periostin controls keratinocyte proliferation and differentiation by interacting with the paracrine IL-1?/IL-6 loop. J Invest Dermatol. 2014;134:1295-1304 pubmed publisher
Wu W, Mehta H, Chakrabarty K, Booth J, Duggan E, Patel K, et al. Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin. J Immunol. 2009;183:5799-806 pubmed publisher
Nold Petry C, Nold M, Nielsen J, Bustamante A, Zepp J, Storm K, et al. Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling. J Biol Chem. 2009;284:25900-11 pubmed publisher
Bitko V, Musiyenko A, Barik S. Viral infection of the lungs through the eye. J Virol. 2007;81:783-90 pubmed
product information
master code :
MAB400
SKU :
MAB400-100
product name :
Mouse IL-1 alpha /IL-1F1 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Mouse IL-1 alpha /IL-1F1 Antibody from R&D Systems is a rat monoclonal antibody to IL-1 alpha/IL-1F1. This antibody reacts with mouse. The Mouse IL-1 alpha /IL-1F1 Antibody has been validated for the following applications: Bioassay,ELISA Development,ELISA Development (Capture),Neutralization,ELISA Capture (Matched Antibody Pair).
target :
IL-1 alpha/IL-1F1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
40508
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse IL-1 alpha /IL-1F1, Ser115-Ser270, Accession # P01582
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse IL-1 alpha /IL-1F1 in ELISAs. In ELISAs, less than 1% cross-reactivity with recombinant rat IL-1 alpha /IL-1F1, recombinant porcine IL-1 alpha /IL-1F1, and recombinant human IL-1 alpha /IL-1F1 is observed.
gene symbol :
IL1A
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by IL-1a/IL-1F1 and Neutralization by Mouse IL-1a/IL-1F1 Antibody.
accessionNumbers :
P01582
applications :
Bioassay,ELISA Development,ELISA Development (Capture),Neutralization,ELISA Capture (Matched Antibody Pair)
USD :
479 USD
alt names :
BAF, Hematopoietin-1, IL1, IL1 alpha, IL-1 alpha, IL1A, IL-1A, IL1-ALPHA, IL1F1, IL-1F1, IL1F1hematopoietin-1, interleukin 1, alpha, interleukin-1 alpha, LAF, LEM, preinterleukin 1 alpha, pro-interleukin-1-alpha
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.