Human Leptin/OB Antibody | R&D Systems MAB398-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Leptin/OB Antibody

catalog :

MAB398-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

44802

reactivity :

human

application :

ELISA, neutralization

more info or order :

R&D Systems product webpage

citations: 21

Reference
Wei J, Huang X, Zhang X, Chen G, Zhang C, Zhou X, et al. Elevated fatty acid β-oxidation by leptin contributes to the proinflammatory characteristics of fibroblast-like synoviocytes from RA patients via LKB1-AMPK pathway. Cell Death Dis. 2023;14:97 pubmed publisher
Crabtree D, Buosi W, Fyfe C, Horgan G, Manios Y, Androutsos O, et al. Appetite Control across the Lifecourse: The Acute Impact of Breakfast Drink Quantity and Protein Content. The Full4Health Project. Nutrients. 2020;12: pubmed publisher
Chang J, Chang E, Lee Y, Cha Y, Cha S, Cho W, et al. Hyperbaric Oxygen Exposure Attenuates Circulating Stress Biomarkers: A Pilot Interventional Study. Int J Environ Res Public Health. 2020;17: pubmed publisher
Patel S, Alvarez Guaita A, Melvin A, Rimmington D, Dattilo A, Miedzybrodzka E, et al. GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans. Cell Metab. 2019;: pubmed publisher
Phillips E, Horniblow R, Poole V, Bedford M, Ward D, Kirkham A, et al. A potential role for hepcidin in obesity-driven colorectal tumourigenesis. Oncol Rep. 2018;39:392-400 pubmed publisher
Tomabechi Y, Tsuruta T, Saito S, Wabitsch M, Sonoyama K. Extra-adrenal glucocorticoids contribute to the postprandial increase of circulating leptin in mice. J Cell Commun Signal. 2018;12:433-439 pubmed publisher
Pashos N, Scarritt M, Eagle Z, Gimble J, Chaffin A, Bunnell B. Characterization of an Acellular Scaffold for a Tissue Engineering Approach to the Nipple-Areolar Complex Reconstruction. Cells Tissues Organs. 2017;203:183-193 pubmed publisher
Molek P, Bratkovi x10d T. Epitope Mapping of Mono- and Polyclonal Antibodies by Screening Phage-displayed Random Peptide Libraries. Acta Chim Slov. 2016;63:914-919 pubmed
Procaccini C, Carbone F, Di Silvestre D, Brambilla F, De Rosa V, Galgani M, et al. The Proteomic Landscape of Human ExÂ Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements. Immunity. 2016;44:406-21 pubmed publisher
Mok J, Mindrinos M, Davis R, Javanmard M. Digital microfluidic assay for protein detection. Proc Natl Acad Sci U S A. 2014;111:2110-5 pubmed publisher
Carbone F, De Rosa V, Carrieri P, Montella S, Bruzzese D, Porcellini A, et al. Regulatory T cell proliferative potential is impaired in human autoimmune disease. Nat Med. 2014;20:69-74 pubmed publisher
Gerrits A, Gitz E, Koekman C, Visseren F, van Haeften T, Akkerman J. Induction of insulin resistance by the adipokines resistin, leptin, plasminogen activator inhibitor-1 and retinol binding protein 4 in human megakaryocytes. Haematologica. 2012;97:1149-57 pubmed publisher
Zhao X, Qureshi F, Eastman P, Manning W, Alexander C, Robinson W, et al. Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis. J Immunol Methods. 2012;378:72-80 pubmed publisher
BORCHERDING D, Hugo E, Idelman G, De Silva A, Richtand N, Loftus J, et al. Dopamine receptors in human adipocytes: expression and functions. PLoS ONE. 2011;6:e25537 pubmed publisher
Schipper H, de Jager W, van Dijk M, Meerding J, Zelissen P, Adan R, et al. A multiplex immunoassay for human adipokine profiling. Clin Chem. 2010;56:1320-8 pubmed publisher
Hu H, Kwun J, Aizenstein B, Knechtle S. Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation. 2009;87:1814-20 pubmed publisher
Madsen E, Bruun J, Skogstrand K, Hougaard D, Christiansen T, Richelsen B. Long-term weight loss decreases the nontraditional cardiovascular risk factors interleukin-18 and matrix metalloproteinase-9 in obese subjects. Metabolism. 2009;58:946-53 pubmed publisher
Sabatier M, McCully K, Marinik E, Schwark E, Haddow S, Cortez Cooper M, et al. Leptin, blood pressure, and aerobic capacity in women. Am J Hypertens. 2008;21:1245-50 pubmed publisher
Emsley H, Smith C, Gavin C, Georgiou R, Vail A, Barberan E, et al. Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production. BMC Neurol. 2007;7:5 pubmed
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product information

master code :

MAB398

SKU :

MAB398-100

product name :

Human Leptin/OB Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human Leptin/OB Antibody from R&D Systems is a mouse monoclonal antibody to Leptin/OB. This antibody reacts with human,n/a. The Human Leptin/OB Antibody has been validated for the following applications: Neutralization,Immunoprecipitation,Antibody Array Development,ELISA (Capture),ELISA Development,Immunoassay Development,Luminex Development,ELISA Capture (Matched Antibody Pair).

target :

Leptin/OB

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

44802

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human Leptin/OB, Val22-Cys167, Accession # P41159

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,N/A

specificity :

Captures human Leptin/OB in sandwich ELISAs. In this format, this antibody shows less than 0.1% cross-reactivity with recombinant mouse (rm) Leptin/OB and rrLeptin/OB.

gene symbol :

LEP

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by Leptin/OB and Neutralization by Human Leptin/OB Antibody.

accessionNumbers :

P41159

applications :

Neutralization,Antibody Array Development,ELISA (Capture),ELISA Development,Immunoassay Development,Luminex Development,ELISA Capture (Matched Antibody Pair)

USD :

479 USD

alt names :

FLJ94114, LEP, leptin, leptin (murine obesity homolog), leptin (obesity homolog, mouse), OB, Obese protein, obese, mouse, homolog of, Obesity factor, OBOBS

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage