Human Matriptase/ST14 Catalytic Domain Antibody | R&D Systems MAB3946 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Matriptase/ST14 Catalytic Domain Antibody

catalog :

MAB3946

quantity :

100 ug (also 25 ug)

price :

449 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

416802

reactivity :

human

application :

western blot, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 4

Reference
Kim J, Park J, Noh E, Song H, Kang S, Jung S, et al. Downregulation of matriptase suppresses the PAR‑2/PLCγ2/PKC‑mediated invasion and migration abilities of MCF‑7 breast cancer cells. Oncol Rep. 2021;46: pubmed publisher
Hwang S, Kim H, Min M, Raghunathan R, Panova I, Munshi R, et al. Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma. J Invest Dermatol. 2015;135:2283-2291 pubmed publisher
Zoratti G, Tanabe L, Varela F, Murray A, Bergum C, Colombo Ã, et al. Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling. Nat Commun. 2015;6:6776 pubmed publisher
Clark E, Jovov B, Rooj A, Fuller C, Benos D. Proteolytic cleavage of human acid-sensing ion channel 1 by the serine protease matriptase. J Biol Chem. 2010;285:27130-43 pubmed publisher

product information

master code :

MAB3946

SKU :

MAB3946

product name :

Human Matriptase/ST14 Catalytic Domain Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Matriptase/ST14 Catalytic Domain Antibody from R&D Systems is a mouse monoclonal antibody to Matriptase/ST14. This antibody reacts with human. The Human Matriptase/ST14 Catalytic Domain Antibody has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Intracellular Staining by Flow Cytometry,CyTOF-ready.

target :

Matriptase/ST14

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

416802

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human Matriptase/ST14 Catalytic Domain, Val615-Val855, Accession # Q9Y5Y6

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Matriptase/ST14 Catalytic Domain in direct ELISAs and Western blots.

gene symbol :

ST14

top caption :

Detection of Matriptase/ST14 antibody in PC-3 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

Q9Y5Y6

applications :

Western Blot,Immunohistochemistry-Paraffin,Intracellular Staining by Flow Cytometry,CyTOF-ready

USD :

449 USD

alt names :

EC 3.4.21, Epithin, HAI, Matriptase, Membrane-type serine protease 1, MTSP1, MT-SP1EC 3.4.21.109, prostamin, PRSS14, Serine protease 14, Serine protease TADG-15, SNC19, SNC19MTSP1, ST14, suppression of tumorigenicity 14 (colon carcinoma), suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin), suppressor of tumorigenicity 14 protein, TADG15, TADG-15, TMPRSS14, tumor associated differentially expressed gene 15 protein, Tumor-associated differentially-expressed gene 15 protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage