Mouse Thrombomodulin/BDCA-3 Antibody | R&D Systems MAB3894 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Thrombomodulin/BDCA-3 Antibody

catalog :

MAB3894

quantity :

100 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

461714

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 5

Reference
Perico L, Morigi M, Pezzotta A, Locatelli M, Imberti B, Corna D, et al. SARS-CoV-2 spike protein induces lung endothelial cell dysfunction and thrombo-inflammation depending on the C3a/C3a receptor signalling. Sci Rep. 2023;13:11392 pubmed publisher
Cai X, Panicker S, Biswas I, Giri H, Rezaie A. Protective Role of Activated Protein C against Viral Mimetic Poly(I:C)-Induced Inflammation. Thromb Haemost. 2021;121:1448-1463 pubmed publisher
May O, Merle N, Grunenwald A, Gnemmi V, Leon J, Payet C, et al. Heme Drives Susceptibility of Glomerular Endothelium to Complement Overactivation Due to Inefficient Upregulation of Heme Oxygenase-1. Front Immunol. 2018;9:3008 pubmed publisher
Satoh T, Satoh K, Yaoita N, Kikuchi N, Omura J, Kurosawa R, et al. Activated TAFI Promotes the Development of Chronic Thromboembolic Pulmonary Hypertension: A Possible Novel Therapeutic Target. Circ Res. 2017;120:1246-1262 pubmed publisher
Belcher J, Chen C, Nguyen J, Milbauer L, Abdulla F, Alayash A, et al. Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease. Blood. 2014;123:377-90 pubmed publisher

product information

master code :

MAB3894

SKU :

MAB3894

product name :

Mouse Thrombomodulin/BDCA-3 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Thrombomodulin/BDCA-3 Antibody from R&D Systems is a rat monoclonal antibody to Thrombomodulin/BDCA-3. This antibody reacts with mouse,transgenic mouse. The Mouse Thrombomodulin/BDCA-3 Antibody has been validated for the following applications: Bioassay,Immunohistochemistry,Immunohistochemistry-Paraffin,Flow Cytometry,Western Blot,Immunocytochemistry,CyTOF-ready.

target :

Thrombomodulin/BDCA-3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

461714

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Thrombomodulin/BDCA-3, Leu17-Ser517, Accession # P15306

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse,Transgenic Mouse

specificity :

Detects mouse Thrombomodulin/BDCA-3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Thrombomodulin is observed.

gene symbol :

THBD

top caption :

Thrombomodulin/BDCA-3 antibody in bEnd by Immunocytochemistry (ICC).3 Mouse Cell Line by Immunocytochemistry (ICC).

accessionNumbers :

P15306

applications :

Bioassay,Immunohistochemistry,Immunohistochemistry-Paraffin,Flow Cytometry,Western Blot,Immunocytochemistry,CyTOF-ready

USD :

439 USD

alt names :

BDCA3, BDCA-3, CD141, CD141 antigen, fetomodulin, THBD, THRM, thrombomodulin, TM

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage