Human Latent TGF┐▀ bp1 Antibody | R&D Systems MAB388-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Latent TGF┐▀ bp1 Antibody

catalog :

MAB388-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

35409

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 11

Reference
Alshawaf A, Viventi S, Qiu W, D Abaco G, Nayagam B, Erlichster M, et al. Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells. Sci Rep. 2018;8:603 pubmed publisher
Sarper M, Cortés E, Lieberthal T, Del RÃo HernÃ¡ndez A. ATRA modulates mechanical activation of TGF-Î² by pancreatic stellate cells. Sci Rep. 2016;6:27639 pubmed publisher
Klingberg F, Chow M, Koehler A, Boo S, Buscemi L, Quinn T, et al. Prestress in the extracellular matrix sensitizes latent TGF-Î²1 for activation. J Cell Biol. 2014;207:283-97 pubmed publisher
Kast J, Hanecker P, Beaufort N, Giese A, Joutel A, Dichgans M, et al. Sequestration of latent TGF-Î² binding protein 1 into CADASIL-related Notch3-ECD deposits. Acta Neuropathol Commun. 2014;2:96 pubmed publisher
Brophy T, Coller B, Ahamed J. Identification of the thiol isomerase-binding peptide, mastoparan, as a novel inhibitor of shear-induced transforming growth factor ?1 (TGF-?1) activation. J Biol Chem. 2013;288:10628-39 pubmed publisher
Willet J, Pichitsiri W, Jenkinson S, Brain J, Wood K, Alhasan A, et al. Kidney transplantation: analysis of the expression and T cell-mediated activation of latent TGF-β. J Leukoc Biol. 2013;93:471-8 pubmed publisher
Shen M, Siu S, Byrd S, Edelmann K, Patel N, Ketchem R, et al. Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31. Exp Cell Res. 2011;317:976-93 pubmed publisher
Massam Wu T, Chiu M, Choudhury R, Chaudhry S, Baldwin A, McGovern A, et al. Assembly of fibrillin microfibrils governs extracellular deposition of latent TGF beta. J Cell Sci. 2010;123:3006-18 pubmed publisher
Vehviläinen P, Hyytiäinen M, Keski Oja J. Matrix association of latent TGF-beta binding protein-2 (LTBP-2) is dependent on fibrillin-1. J Cell Physiol. 2009;221:586-93 pubmed publisher
Gomez D, Al Haj Zen A, Borges L, Philippe M, Gutierrez P, Jondeau G, et al. Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway. J Pathol. 2009;218:131-42 pubmed publisher
Torrealba J, Katayama M, Fechner J, Jankowska Gan E, Kusaka S, Xu Q, et al. Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates. J Immunol. 2004;172:5753-64 pubmed

product information

master code :

MAB388

SKU :

MAB388-100

product name :

Human Latent TGF┐▀ bp1 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human Latent TGF¿ß bp1 Antibody from R&D Systems is a mouse monoclonal antibody to Latent TGF-beta bp1. This antibody reacts with human,primate - macaca mulatta (rhesus macaque),rat. The Human Latent TGF¿ß bp1 Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoaffinity Purification.

target :

Latent TGF-beta bp1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

35409

conjugate :

Unconjugated

host :

Mouse

immunogen :

Human platelet-derived large latent TGF┐▀1 complex

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human,Primate - Macaca mulatta (Rhesus Macaque)

specificity :

Detects human LTBP-1 from the large latent TGF┐▀1 complex.

gene symbol :

LTBP1

applications :

Immunoprecipitation,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Immunoaffinity Purification

USD :

459 USD

alt names :

Latent TGFbeta bp1, latent transforming growth factor beta binding protein 1, latent-transforming growth factor beta-binding protein 1, LTBP1, LTBP-1, MGC163161, TGF-beta1-BP-1, Transforming growth factor beta-1-binding protein 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage