Mouse Nectin-2/CD112 Antibody | R&D Systems MAB3869 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Nectin-2/CD112 Antibody

catalog :

MAB3869

quantity :

100 ug (also 25 ug)

price :

459 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

829038

reactivity :

mouse

application :

immunohistochemistry, neutralization, flow cytometry, blocking or activating experiments

more info or order :

R&D Systems product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; mouse	Ho D, Tsui Y, Chan L, Sze K, Zhang X, Cheu J, et al. Single-cell RNA sequencing shows the immunosuppressive landscape and tumor heterogeneity of HBV-associated hepatocellular carcinoma. Nat Commun. 2021;12:3684 pubmed publisher
	Skurikhin E, Pershina O, Zhukova M, Widera D, Pan E, Pakhomova A, et al. Spiperone Stimulates Regeneration in Pulmonary Endothelium Damaged by Cigarette Smoke and Lipopolysaccharide. Int J Chron Obstruct Pulmon Dis. 2021;16:3575-3591 pubmed publisher
	Russo E, Runge P, Jahromi N, Naboth H, Landtwing A, Montecchi R, et al. CD112 Regulates Angiogenesis and T Cell Entry into the Spleen. Cells. 2021;10: pubmed publisher
	Nakamura Y, Miyagawa S, Yoshida S, Sasawatari S, Toyofuku T, Toda K, et al. Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model. Sci Rep. 2019;9:10840 pubmed publisher
	Ott M, Avendaño Guzmán E, Ullrich E, Dreyer C, Strauss J, Harden M, et al. Laquinimod, a prototypic quinoline-3-carboxamide and aryl hydrocarbon receptor agonist, utilizes a CD155-mediated natural killer/dendritic cell interaction to suppress CNS autoimmunity. J Neuroinflammation. 2019;16:49 pubmed publisher
	Zhang Q, Bi J, Zheng X, Chen Y, Wang H, Wu W, et al. Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity. Nat Immunol. 2018;19:723-732 pubmed publisher
	Nakata J, Nakano K, Okumura A, Mizutani Y, Kinoshita H, Iwai M, et al. In vivo eradication of MLL/ENL leukemia cells by NK cells in the absence of adaptive immunity. Leukemia. 2014;28:1316-25 pubmed publisher

product information

master code :

MAB3869

SKU :

MAB3869

product name :

Mouse Nectin-2/CD112 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Nectin-2/CD112 Antibody from R&D Systems is a rat monoclonal antibody to Nectin-2/CD112. This antibody reacts with mouse. The Mouse Nectin-2/CD112 Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Immunohistochemistry,CyTOF-ready.

target :

Nectin-2/CD112

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

829038

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Nectin-2/CD112, Gln32-Gly351 (predicted), Accession # P32507

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse Nectin-2/CD112 in ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Nectin-2 or recombinant mouse CD155/PVR is observed.

gene symbol :

PVRL2

top caption :

Detection of Nectin-2/CD112 antibody in C2C12 Mouse Cell Line antibody by Flow Cytometry.

accessionNumbers :

P32507

applications :

Flow Cytometry,Neutralization,Immunohistochemistry,CyTOF-ready

USD :

459 USD

alt names :

CD112, CD112 antigen, Herpes virus entry mediator B, Herpesvirus entry mediator B, herpesvirus entry protein B, HVEB, HVEBpoliovirus receptor-like 2, MPH, nectin 2, Nectin2, Nectin-2, poliovirus receptor-related 2 (herpesvirus entry mediator B), poliovirus receptor-related protein 2, PRR2, PRR2nectin-2, PVRL2, PVRR2poliovirus receptor related 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage