Human CD14 Antibody | R&D Systems MAB3832-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CD14 Antibody

catalog :

MAB3832-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

134620

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 24

Reference
Evans L, Gawron J, Sim F, Feltri M, Marziali L. Human iPSC-derived myelinating organoids and globoid cells to study Krabbe Disease. bioRxiv. 2024;: pubmed publisher
Choe U, Pham Q, Kim Y, Yu L, Wang T. Identification and elucidation of cross talk between SLAM Family Member 7 (SLAMF7) and Toll-like receptor (TLR) pathways in monocytes and macrophages. Sci Rep. 2023;13:11007 pubmed publisher
Fowler T, Choudhary V, Melnyk S, Farsi M, Chang L, Fortingo N, et al. Dioleoylphosphatidylglycerol Inhibits Heat Shock Protein B4 (HSPB4)-Induced Inflammatory Pathways In Vitro. Int J Mol Sci. 2023;24: pubmed publisher
Njau F, Haller H. Calcium Dobesilate Modulates PKCδ-NADPH Oxidase- MAPK-NF-κB Signaling Pathway to Reduce CD14, TLR4, and MMP9 Expression during Monocyte-to-Macrophage Differentiation: Potential Therapeutic Implications for Atherosclerosis. Antioxidants (Basel). 2021;10: pubmed publisher
Jun J, Lau L. CCN1 is an opsonin for bacterial clearance and a direct activator of Toll-like receptor signaling. Nat Commun. 2020;11:1242 pubmed publisher
Yagnik D, Hills F. Urate crystals induce macrophage PAF‑AH secretion which is differentially regulated by TGFβ1 and hydrocortisone. Mol Med Rep. 2018;18:3506-3512 pubmed publisher
Kita M, Yokota K, Kageyama C, Take S, Goto K, Kawahara Y, et al. DEC205 mediates local and systemic immune responses to Helicobacter pylori infection in humans. Oncotarget. 2018;9:15828-15835 pubmed publisher
Yu L, Yu L, Pham Q, Wang T. Transcriptional and translational-uncoupling in regulation of the CXCL12 and its receptors CXCR4, 7 in THP-1 monocytes and macrophages. Immun Inflamm Dis. 2017;: pubmed publisher
Walters B, Uynuk Ool T, Rothdiener M, Palm J, Hart M, Stegemann J, et al. Engineering the geometrical shape of mesenchymal stromal cells through defined cyclic stretch regimens. Sci Rep. 2017;7:6640 pubmed publisher
Hisada Y, Auriemma A, Alexander W, Ay C, Mackman N. Detection of tissue factor-positive extracellular vesicles by laser scanning confocal microscopy. Thromb Res. 2017;150:65-72 pubmed publisher
Wensink A, Kok H, Meeldijk J, Fermie J, Froelich C, Hack C, et al. Granzymes A and K differentially potentiate LPS-induced cytokine response. Cell Death Discov. 2016;2:16084 pubmed publisher
Odent Grigorescu G, Rosca A, Preda M, Tutuianu R, Simionescu M, Burlacu A. Synergic effects of VEGF-A and SDF-1 on the angiogenic properties of endothelial progenitor cells. J Tissue Eng Regen Med. 2017;11:3241-3252 pubmed publisher
Zhang Y, Vernooij F, Ibrahim I, Ooi S, Gijsberts C, Schoneveld A, et al. Extracellular Vesicle Proteins Associated with Systemic Vascular Events Correlate with Heart Failure: An Observational Study in a Dyspnoea Cohort. PLoS ONE. 2016;11:e0148073 pubmed publisher
Stein E, Miller T, Ivins O Keefe K, Kaur S, Roberts D. Secreted Thrombospondin-1 Regulates Macrophage Interleukin-1Î² Production and Activation through CD47. Sci Rep. 2016;6:19684 pubmed publisher
Young O, Tang Z, Niven Fairchild T, Tadesse S, Krikun G, Norwitz E, et al. Toll-like receptor-mediated responses by placental Hofbauer cells (HBCs): a potential pro-inflammatory role for fetal M2 macrophages. Am J Reprod Immunol. 2015;73:22-35 pubmed publisher
Huizinga R, van Rijs W, Bajramovic J, Kuijf M, Laman J, Samsom J, et al. Sialylation of Campylobacter jejuni endotoxin promotes dendritic cell-mediated B cell responses through CD14-dependent production of IFN-? and TNF-?. J Immunol. 2013;191:5636-45 pubmed publisher
Kothari H, Rao L, Vankayalapati R, Pendurthi U. Mycobacterium tuberculosis infection and tissue factor expression in macrophages. PLoS ONE. 2012;7:e45700 pubmed publisher
Puddu P, Latorre D, Carollo M, Catizone A, Ricci G, Valenti P, et al. Bovine lactoferrin counteracts Toll-like receptor mediated activation signals in antigen presenting cells. PLoS ONE. 2011;6:e22504 pubmed publisher
Pilz G, Braun J, Ulrich C, Felka T, Warstat K, Ruh M, et al. Human mesenchymal stromal cells express CD14 cross-reactive epitopes. Cytometry A. 2011;79:635-45 pubmed publisher
Chui J, Li M, Di Girolamo N, Chang J, McCluskey P, Wakefield D. Iris pigment epithelial cells express a functional lipopolysaccharide receptor complex. Invest Ophthalmol Vis Sci. 2010;51:2558-67 pubmed publisher
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Yu L, Turner J, Buret A. LPS/CD14 activation triggers SGLT-1-mediated glucose uptake and cell rescue in intestinal epithelial cells via early apoptotic signals upstream of caspase-3. Exp Cell Res. 2006;312:3276-86 pubmed

product information

brand :

R&D Systems

master code :

MAB3832

SKU :

MAB3832-100

product name :

Human CD14 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human CD14 Antibody from R&D Systems is a mouse monoclonal antibody to CD14. This antibody reacts with human. The Human CD14 Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,ELISA Development,Flow Cytometry,Western Blot,Neutralization,CyTOF-ready.

target :

CD14

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

134620

conjugate :

Unconjugated

dilution :

Western Blot 2 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunohistochemistry 5-25 ug/mL, Neutralization 10 ug/mL, CyTOF-ready

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human CD14, Thr20-Cys352, Accession # P08571

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human CD14 in direct ELISAs and Western blots.

gene symbol :

CD14

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

accessionNumbers :

P08571

applications :

CyTOF-ready,ELISA Development,Flow Cytometry,Immunohistochemistry,Western Blot,Neutralization,Immunocytochemistry

USD :

489 USD

alt names :

CD14, CD14 antigen, CD14 molecule, monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage