product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CD27/TNFRSF7 Antibody
catalog :
MAB382-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
57703
reactivity :
human
application :
western blot, neutralization, flow cytometry
more info or order :
citations: 4
Reference
Van den Eynde A, Gehrcken L, Verhezen T, Lau H, Hermans C, Lambrechts H, et al. IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts. J Hematol Oncol. 2024;17:8 pubmed publisher
Abe Y, Sakata Yanagimoto M, Fujisawa M, Miyoshi H, Suehara Y, Hattori K, et al. A single-cell atlas of non-haematopoietic cells in human lymph nodes and lymphoma reveals a landscape of stromal remodelling. Nat Cell Biol. 2022;24:565-578 pubmed publisher
Boccazzi M, Van Steenwinckel J, Schang A, Faivre V, Le Charpentier T, Bokobza C, et al. The immune-inflammatory response of oligodendrocytes in a murine model of preterm white matter injury: the role of TLR3 activation. Cell Death Dis. 2021;12:166 pubmed publisher
Vranjkovic A, Crawley A, Gee K, Kumar A, Angel J. IL-7 decreases IL-7 receptor alpha (CD127) expression and induces the shedding of CD127 by human CD8+ T cells. Int Immunol. 2007;19:1329-39 pubmed
product information
master code :
MAB382
SKU :
MAB382-100
product name :
Human CD27/TNFRSF7 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human CD27/TNFRSF7 Antibody from R&D Systems is a mouse monoclonal antibody to CD27/TNFRSF7. This antibody reacts with human. The Human CD27/TNFRSF7 Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Western Blot,CyTOF-ready.
target :
CD27/TNFRSF7
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
57703
conjugate :
Unconjugated
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human CD27, Thr21-Ile192, Accession # P26842
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human CD27 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) 4-1BB, rhBAFF R, recombinant mouse (rm) CD27, rhCD30, rhCD40, rhDR3, rhDR6, rhEDAR, rhFas, rhGITR, rhHVEM, rhLTR▀, rhNGF R, rhOPG, rmOX40, rhRANK, rhTAJ, or rhTNF RI is observed.
gene symbol :
CD27
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
CD27/TNFRSF7 Inhibition of CD27 Ligand/TNFSF7-dependent Cell Proliferation and Neutralization by Human CD27/TNFRSF7 Antibody.
accessionNumbers :
P26842
applications :
Flow Cytometry,Neutralization,Western Blot,CyTOF-ready
USD :
469 USD
alt names :
CD27, CD27 antigen, CD27 molecule, MGC20393, S152CD27L receptor, T cell activation antigen CD27, T cell activation antigen S152, T14, TNFRSF7, TNFRSF7T-cell activation antigen CD27, Tp55, Tumor necrosis factor receptor superfamily member 7, tumor necrosis factor receptor superfamily, member 7
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.