This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human NRG1-beta 1/HRG1-beta 1 EGF Domain Antibody
catalog :
MAB3771
quantity :
100 ug (also 25 ug, 500 ug)
price :
359 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
147705
reactivity :
human
citations: 3
Reference
Guven A, Kalebic N, Long K, Florio M, Vaid S, Brandl H, et al. Extracellular matrix-inducing Sox9 promotes both basal progenitor proliferation and gliogenesis in developing neocortex. elife. 2020;9: pubmed publisher
Lemmens K, Doggen K, De Keulenaer G. Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy. Am J Physiol Heart Circ Physiol. 2011;300:H931-42 pubmed publisher
Sheng Q, Liu X, Fleming E, Yuan K, Piao H, Chen J, et al. An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells. Cancer Cell. 2010;17:298-310 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB3771
SKU :
MAB3771-100
product name :
Human NRG1-beta 1/HRG1-beta 1 EGF Domain Antibody
description :
The Human NRG1-beta 1/HRG1-beta 1 EGF Domain Antibody from R&D Systems is a mouse monoclonal antibody to Neuregulin-1 beta 1/NRG1 beta 1. This antibody reacts with human. The Human NRG1-beta 1/HRG1-beta 1 EGF Domain Antibody has been validated for the following applications: ELISA Capture (Matched Antibody Pair).
target :
Neuregulin-1 beta 1/NRG1 beta 1
category :
Primary Antibodies
unit size :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
147705
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human NRG1-beta 1/HRG1-beta 1, Ser2-Lys246, Accession # AAA58639
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human NRG1-beta 1 in ELISAs. Recognizes an epitope found in the EGF-like domain of NRG1-beta 1 (amino acids 179-246). It also detects recombinant human SMDF (Sensory and Motor neuron-Derived Factor), but it does not recognize the EGF-like domain of human NRG1-alpha (amino acids 177-241). The epitope is present within amino acids 213-230 of human NRG1-beta 1. This segment is present in all NRG1 beta isoforms, GGF-2 (glial growth factor), and SMDF, but it is absent from NRG1-alpha , NDF43, and NRG1-gamma .
gene symbol :
NRG1
catalog number base :
MAB3771
accessionNumbers :
AAA58639
applications :
ELISA Capture (Matched Antibody Pair)
2020 USD :
339
2021 USD :
359 USD
alt names :
ARIA, GGF, GGF2, Heregulin-1, HGL, HRG, HRG1, HRG1-alpha, HRG1-beta 1, HRGA, MST131, MSTP131, NDF, neuregulin 1, Neuregulin1, Neuregulin1 beta 1, NRG1, NRG1-IT2, SMDF
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.