Human NRG1┐▀1/HRG1┐▀1 EGF Domain Antibody | R&D Systems MAB3771-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human NRG1┐▀1/HRG1┐▀1 EGF Domain Antibody

catalog :

MAB3771-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

147705

reactivity :

human, rat

application :

western blot, ELISA

more info or order :

R&D Systems product webpage

citations: 2

Reference
Lemmens K, Doggen K, De Keulenaer G. Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy. Am J Physiol Heart Circ Physiol. 2011;300:H931-42 pubmed publisher
Sheng Q, Liu X, Fleming E, Yuan K, Piao H, Chen J, et al. An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells. Cancer Cell. 2010;17:298-310 pubmed publisher

product information

master code :

MAB3771

SKU :

MAB3771-100

product name :

Human NRG1┐▀1/HRG1┐▀1 EGF Domain Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human NRG1¿ß1/HRG1¿ß1 EGF Domain Antibody from R&D Systems is a mouse monoclonal antibody to Neuregulin-1 beta 1/NRG1 beta 1. This antibody reacts with human,mouse,rat. The Human NRG1¿ß1/HRG1¿ß1 EGF Domain Antibody has been validated for the following applications: Western Blot,ELISA Capture (Matched Antibody Pair).

target :

Neuregulin-1 beta 1/NRG1 beta 1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

147705

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human NRG1┐▀1/HRG1┐▀1, Ser2-Lys246, Accession # AAA58639

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects human NRG1┐▀1 in ELISAs. Recognizes an epitope found in the EGF-like domain of NRG1┐▀1 (amino acids 179-246). It also detects recombinant human SMDF (Sensory and Motor neuron-Derived Factor), but it does not recognize the EGF-like domain of human NRG1-alpha (amino acids 177-241). The epitope is present within amino acids 213-230 of human NRG1┐▀1. This segment is present in all NRG1 beta isoforms, GGF-2 (glial growth factor), and SMDF, but it is absent from NRG1-alpha , NDF43, and NRG1-gamma .

gene symbol :

NRG1

accessionNumbers :

AAA58639

applications :

Western Blot,ELISA Capture (Matched Antibody Pair)

USD :

459 USD

alt names :

ARIA, GGF, GGF2, Heregulin-1, HGL, HRG, HRG1, HRG1-alpha, HRG1-beta 1, HRGA, MST131, MSTP131, NDF, neuregulin 1, Neuregulin1, Neuregulin1 beta 1, NRG1, NRG1-IT2, SMDF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage