Human/Mouse RUNX3/CBFA3 Antibody | R&D Systems MAB3765 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse RUNX3/CBFA3 Antibody

catalog :

MAB3765

quantity :

100 ug (also 25 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

527327

reactivity :

human, mouse

application :

western blot, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Yang W, Wang Y, Du Y, Li J, Jia M, Li S, et al. Chemical reprogramming of melanocytes to skeletal muscle cells. J Cachexia Sarcopenia Muscle. 2023;14:903-914 pubmed publisher
Facciotti F, Larghi P, Bosotti R, Vasco C, Gagliani N, Cordiglieri C, et al. Evidence for a pathogenic role of extrafollicular, IL-10-producing CCR6+B helper T cells in systemic lupus erythematosus. Proc Natl Acad Sci U S A. 2020;117:7305-7316 pubmed publisher
Balogh P, Adelman E, Pluvinage J, Capaldo B, Freeman K, Singh S, et al. RUNX3 levels in human hematopoietic progenitors are regulated by aging and dictate erythroid-myeloid balance. Haematologica. 2019;: pubmed publisher
Choi A, Illendula A, Pulikkan J, Roderick J, Tesell J, Yu J, et al. RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia. Blood. 2017;130:1722-1733 pubmed publisher
Chopin M, Seillet C, Chevrier S, Wu L, Wang H, Morse H, et al. Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks. J Exp Med. 2013;210:2967-80 pubmed publisher
Giambra V, Jenkins C, Wang H, Lam S, Shevchuk O, Nemirovsky O, et al. NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-? and reactive oxygen species. Nat Med. 2012;18:1693-8 pubmed publisher

product information

master code :

MAB3765

SKU :

MAB3765

product name :

Human/Mouse RUNX3/CBFA3 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse RUNX3/CBFA3 Antibody from R&D Systems is a mouse monoclonal antibody to RUNX3/CBFA3. This antibody reacts with human,mouse. The Human/Mouse RUNX3/CBFA3 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunocytochemistry,Simple Western,Intracellular Staining by Flow Cytometry,CyTOF-ready.

target :

RUNX3/CBFA3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

527327

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human RUNX3/CBFA3, Lys186-Tyr415, Accession # Q13761

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human and mouse RUNX3/CBFA3 in Western blots.

gene symbol :

RUNX3

top caption :

Detection of RUNX3/CBFA3 antibody in Human PBMC antibody by Flow Cytometry.

accessionNumbers :

Q13761

applications :

Flow Cytometry,Western Blot,Immunocytochemistry,Simple Western,Intracellular Staining by Flow Cytometry,CyTOF-ready

USD :

459 USD

alt names :

Acute myeloid leukemia 2 protein, AML2, AML2SL3/AKV core-binding factor alpha C subunit, CBFA3, CBFA3MGC16070, CBF-alpha-3, PEA2 alpha C, PEA2-alpha C, PEBP2 alpha C, PEBP2A3, PEBP2A3FLJ34510, PEBP2AC, PEBP2-alpha C, runt domain, alpha subunit 3, runt-related transcription factor 3, SL3-3 enhancer factor 1 alpha C subunit, transcription factor AML2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage