Human CCL27/CTACK Antibody | R&D Systems MAB376-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCL27/CTACK Antibody

catalog :

MAB376-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

124308

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 6

Reference
Karnezis T, Farnsworth R, Harris N, Williams S, Caesar C, Byrne D, et al. CCL27/CCL28-CCR10 Chemokine Signaling Mediates Migration of Lymphatic Endothelial Cells. Cancer Res. 2019;79:1558-1572 pubmed publisher
Yang X, Jiang H, Lei R, Lu W, Tan S, Qin S. Recruitment and significance of Th22 cells and Th17 cells in malignant ascites. Oncol Lett. 2018;16:5389-5397 pubmed publisher
Maghazachi A, Sand K, Al Jaderi Z. Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity. Front Immunol. 2016;7:437 pubmed
Goteri G, Rupoli S, Campanati A, Zizzi A, Picardi P, Cardelli M, et al. Serum and tissue CTACK/CCL27 chemokine levels in early mycosis fungoides may be correlated with disease-free survival following treatment with interferon alfa and psoralen plus ultraviolet A therapy. Br J Dermatol. 2012;166:948-52 pubmed publisher
Kaporis H, Guttman Yassky E, Lowes M, Haider A, Fuentes Duculan J, Darabi K, et al. Human basal cell carcinoma is associated with Foxp3+ T cells in a Th2 dominant microenvironment. J Invest Dermatol. 2007;127:2391-8 pubmed
Fujita Y, Abe R, Sasaki M, Honda A, Furuichi M, Asano Y, et al. Presence of circulating CCR10+ T cells and elevated serum CTACK/CCL27 in the early stage of mycosis fungoides. Clin Cancer Res. 2006;12:2670-5 pubmed

product information

master code :

MAB376

SKU :

MAB376-100

product name :

Human CCL27/CTACK Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human CCL27/CTACK Antibody from R&D Systems is a mouse monoclonal antibody to CCL27/CTACK. This antibody reacts with human,xenograft. The Human CCL27/CTACK Antibody has been validated for the following applications: Granzyme B Activity,Neutralization,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunohistochemistry,Western Blot.

target :

CCL27/CTACK

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

124308

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CCL27/CTACK, Phe25-Gly112, Accession # NP_006655

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Xenograft

specificity :

Detects human CCL27/CTACK in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human CCL1, 2, 3, 4, 5, 7, 8, 11, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, recombinant mouse CCL1, 2, 3, 4, 5, 6, 7, 9/10, 11, 12, 17, 19, 20, 21, 22, 24, 25, or recombinant rat CCL20 is observed.

gene symbol :

CCL27

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Chemotaxis Induced by CCL27/CTACK and Neutralization by Human CCL27/CTACK Antibody.

accessionNumbers :

NP_006655

applications :

Granzyme B Activity,Neutralization,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunohistochemistry,Western Blot

USD :

469 USD

alt names :

ALP, C-C motif chemokine 27, chemokine (C-C motif) ligand 27, CTACK, CTACKSmall-inducible cytokine A27, CTAK, cutaneous T-cell attracting chemokine, Cutaneous T-cell-attracting chemokine, ESKINE, IL-11 Ralpha-locus chemokine, ILC, ILCCC chemokine ILC, PESKY, SCYA27IL-11 R-alpha-locus chemokine, Skinkine, small inducible cytokine subfamily A (Cys-Cys), member 27

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage