Human FPR1 Antibody | R&D Systems MAB3744 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human FPR1 Antibody

catalog :

MAB3744

quantity :

100 ug (also 25 ug)

price :

449 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

350418

reactivity :

human

application :

immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 9

Reference
Busch L, Al Taleb Z, Tsai Y, Nguyen V, Lu Q, Synatschke C, et al. Amyloid beta and its naturally occurring N-terminal variants are potent activators of human and mouse formyl peptide receptor 1. J Biol Chem. 2022;298:102642 pubmed publisher
Itagaki K, Kaczmarek E, Kwon W, Chen L, Vlkova B, Zhang Q, et al. Formyl Peptide Receptor-1 Blockade Prevents Receptor Regulation by Mitochondrial Danger-Associated Molecular Patterns and Preserves Neutrophil Function After Trauma. Crit Care Med. 2020;48:e123-e132 pubmed publisher
Lee H, Jeong Y, Lee M, Kweon H, Huh Y, Park J, et al. Intracellular formyl peptide receptor regulates naÃ¯ve CD4 T cell migration. Biochem Biophys Res Commun. 2018;497:226-232 pubmed publisher
Bufe B, Schumann T, Kappl R, Bogeski I, Kummerow C, PodgÃ³rska M, et al. Recognition of bacterial signal peptides by mammalian formyl peptide receptors: a new mechanism for sensing pathogens. J Biol Chem. 2015;290:7369-87 pubmed publisher
Butler R, Hornigold D, Huang L, Huntington C, London T, Dillon J, et al. Use of the site-specific retargeting jump-in platform cell line to support biologic drug discovery. J Biomol Screen. 2015;20:528-35 pubmed publisher
Douthwaite J, Sridharan S, Huntington C, Hammersley J, Marwood R, Hakulinen J, et al. Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1. MAbs. 2015;7:152-66 pubmed publisher
Prevete N, Liotti F, Visciano C, Marone G, Melillo R, de Paulis A. The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis. Oncogene. 2015;34:3826-38 pubmed publisher
Mintz R, Garty B, Meshel T, Marcus N, Katanov C, Cohen Hillel E, et al. Reduced expression of chemoattractant receptors by polymorphonuclear leukocytes in Hyper IgE Syndrome patients. Immunol Lett. 2010;130:97-106 pubmed publisher
Ishmael S, Macglashan D. Syk expression in peripheral blood leukocytes, CD34+ progenitors, and CD34-derived basophils. J Leukoc Biol. 2010;87:291-300 pubmed publisher

product information

master code :

MAB3744

SKU :

MAB3744

product name :

Human FPR1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human FPR1 Antibody from R&D Systems is a mouse monoclonal antibody to FPR1. This antibody reacts with human. The Human FPR1 Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry,CyTOF-ready.

target :

FPR1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

350418

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

HEK293 human embryonic kidney cell line transfected with human FPR1, Met1-Lys350, Accession # NP_002020

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human FPR1. Stains human FPR1-transfected cells but not irrelevant transfectants.

gene symbol :

FPR1

accessionNumbers :

NP_002020

applications :

Flow Cytometry,Immunocytochemistry,CyTOF-ready

USD :

449 USD

alt names :

fMet-Leu-Phe receptor, fMLF-R, FMLP, fMLP receptor, formyl peptide receptor 1, FPRfMet-Leu-Phe receptor, N-formyl peptide receptor, N-formylpeptide chemoattractant receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage