Human Fibroblast Activation Protein alpha/FAP Antibody | R&D Systems MAB3715 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Fibroblast Activation Protein alpha/FAP Antibody

catalog :

MAB3715

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

427819

reactivity :

human

application :

flow cytometry

citations: 6

Reference
Kieffer Y, Hocine H, Gentric G, Pelon F, Bernard C, Bourachot B, et al. Single-Cell Analysis Reveals Fibroblast Clusters Linked to Immunotherapy Resistance in Cancer. Cancer Discov. 2020;10:1330-1351 pubmed publisher
Pelon F, Bourachot B, Kieffer Y, Magagna I, Mermet Meillon F, Bonnet I, et al. Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms. Nat Commun. 2020;11:404 pubmed publisher
Nguyen M, De Ninno A, Mencattini A, Mermet Meillon F, Fornabaio G, Evans S, et al. Dissecting Effects of Anti-cancer Drugs and Cancer-Associated Fibroblasts by On-Chip Reconstitution of Immunocompetent Tumor Microenvironments. Cell Rep. 2018;25:3884-3893.e3 pubmed publisher
Costa A, Kieffer Y, Scholer Dahirel A, Pelon F, Bourachot B, Cardon M, et al. Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer. Cancer Cell. 2018;33:463-479.e10 pubmed publisher
Witek M, Aufforth R, Wang H, Kamande J, Jackson J, Pullagurla S, et al. Discrete microfluidics for the isolation of circulating tumor cell subpopulations targeting fibroblast activation protein alpha and epithelial cell adhesion molecule. NPJ Precis Oncol. 2017;1: pubmed publisher
Freedman J, Hagel J, Scott E, Psallidas I, Gupta A, Spiers L, et al. Oncolytic adenovirus expressing bispecific antibody targets T-cell cytotoxicity in cancer biopsies. EMBO Mol Med. 2017;9:1067-1087 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB3715

SKU :

MAB3715-100

product name :

Human Fibroblast Activation Protein alpha/FAP Antibody

description :

The Human Fibroblast Activation Protein alpha/FAP Antibody from R&D Systems is a mouse monoclonal antibody to Fibroblast Activation Protein alpha/FAP. This antibody reacts with human. The Human Fibroblast Activation Protein alpha/FAP Antibody has been validated for the following applications: Flow Cytometry, CyTOF-ready, ELISA Capture (Matched Antibody Pair).

target :

Fibroblast Activation Protein alpha/FAP

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

427819

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Fibroblast Activation Protein alpha/FAP, Leu26-Asp760, Accession # Q12884

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Fibroblast Activation Protein alpha/FAP in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human DPP6 and DPP4 is observed.

gene symbol :

FAP

details of functionality :

ActivityAssaywCitation not found None None

catalog number base :

MAB3715

accessionNumbers :

Q12884

applications :

Flow Cytometry, CyTOF-ready, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

369 USD

alt names :

170 kDa melanoma membrane-bound gelatinase, DKFZp686G13158, DPPIV, EC 3.4.21.-, FAP, FAPA, Fibroblast activation protein alpha, fibroblast activation protein, alpha, Integral membrane serine protease, seprase, vibronectin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.