product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CCL21/6Ckine Antibody
catalog :
MAB3661
quantity :
500 ug (also 25 ug)
price :
569 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
54111
reactivity :
human
application :
western blot, ELISA, neutralization
more info or order :
citations: 3
Reference
Yin X, Johns S, Kim D, Mikulski Z, SALANGA C, Handel T, et al. Lymphatic specific disruption in the fine structure of heparan sulfate inhibits dendritic cell traffic and functional T cell responses in the lymph node. J Immunol. 2014;192:2133-42 pubmed publisher
Yin X, Truty J, Lawrence R, Johns S, Srinivasan R, Handel T, et al. A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis. Mol Cancer. 2010;9:316 pubmed publisher
Woolf E, Grigorova I, Sagiv A, Grabovsky V, Feigelson S, Shulman Z, et al. Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces. Nat Immunol. 2007;8:1076-85 pubmed
product information
master code :
MAB3661
SKU :
MAB3661
product name :
Human CCL21/6Ckine Antibody
unit size :
500 ug (also 25 ug)
description :
The Human CCL21/6Ckine Antibody from R&D Systems is a mouse monoclonal antibody to CCL21/6Ckine. This antibody reacts with human. The Human CCL21/6Ckine Antibody has been validated for the following applications: Neutralization,Functional Assay,Western Blot,ELISA Capture (Matched Antibody Pair).
target :
CCL21/6Ckine
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
54111
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human CCL21/6Ckine, Ser24-Pro134, Accession # O00585
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human CCL21/6Ckine in ELISAs and Western blots. In Western blots, shows 100% cross-reactivity with recombinant human (rh) CCL24. Under reducing conditions, shows approximately 10-50% cross-reactivity with rhCCL2, 8, 13, 28, and rmCCL2. Does not cross-react with rhCCL1, 3, 4, 5, 7, 9, 11, 14a, 15, 17, 18, 19, 20, 22, 23, 25, rmCCL1, 3, 4, 6, 7, 9, 11, 12, 19, 20, 21, 22, 24, 25, 28, or rrCCL20.
gene symbol :
CCL21
top caption :
Detection of CCL21/6Ckine by Western Blot
accessionNumbers :
O00585
applications :
Neutralization,Functional Assay,Western Blot,ELISA Capture (Matched Antibody Pair)
USD :
569 USD
alt names :
6Ckine, 6CkineSmall-inducible cytokine A21, Beta-chemokine exodus-2, chemokine (C-C motif) ligand 21, CKb9, exodus-2, member 21, SCYA21, SCYA21MGC34555, secondary lymphoid tissue chemokine, SLC, SLCSecondary lymphoid-tissue chemokine, TCA-4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.