Human CCL21/6Ckine Antibody | R&D Systems MAB366 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCL21/6Ckine Antibody

catalog :

MAB366

quantity :

500 ug (also 25 ug)

price :

569 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

54125

reactivity :

human

application :

western blot, immunocytochemistry, neutralization, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 5

Reference
Didriksen H, Molberg x, Mehta A, Jordan S, Palchevskiy V, Fretheim H, et al. Target organ expression and biomarker characterization of chemokine CCL21 in systemic sclerosis associated pulmonary arterial hypertension. Front Immunol. 2022;13:991743 pubmed publisher
Omland S, Wettergren E, Mollerup S, Asplund M, Mourier T, Hansen A, et al. Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin. BMC Cancer. 2017;17:675 pubmed publisher
Johnson L, Jackson D. Inflammation-induced secretion of CCL21 in lymphatic endothelium is a key regulator of integrin-mediated dendritic cell transmigration. Int Immunol. 2010;22:839-49 pubmed publisher
Birke K, Lütjen Drecoll E, Kerjaschki D, Birke M. Expression of podoplanin and other lymphatic markers in the human anterior eye segment. Invest Ophthalmol Vis Sci. 2010;51:344-54 pubmed publisher
Pierce E, Carpenter K, Jakubzick C, Kunkel S, Flaherty K, Martinez F, et al. Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice. Am J Pathol. 2007;170:1152-64 pubmed

product information

master code :

MAB366

SKU :

MAB366

product name :

Human CCL21/6Ckine Antibody

unit size :

500 ug (also 25 ug)

description :

The Human CCL21/6Ckine Antibody from R&D Systems is a mouse monoclonal antibody to CCL21/6Ckine. This antibody reacts with complex species category,human. The Human CCL21/6Ckine Antibody has been validated for the following applications: Neutralization,Immunohistochemistry-Frozen,Immunocytochemistry,Western Blot.

target :

CCL21/6Ckine

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

54125

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CCL21/6Ckine, Ser24-Pro134, Accession # O00585

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Complex Species Category,Human

specificity :

Detects human CCL21/6Ckine in direct ELISAs and Western blots. Does not cross-react with recombinant mouse (rm) CCL21, recombinant human (rh) MCP-1, rhMCP-2, rhMCP-3, rhMCP-4, rmMCP-5, rhMIP-1 alpha , rmMIP-1 alpha , rhMIP-1▀, rmMIP-1▀, rhMIP-1 delta , rmMIP-1 gamma , rmMIP-2, rhMIP-3 alpha , rmMIP-3 alpha , rrMIP-3 alpha , rhMIP-3▀, rmMIP-3▀, or rmCCL7.

gene symbol :

CCL21

accessionNumbers :

O00585

applications :

Neutralization,Immunohistochemistry-Frozen,Immunocytochemistry,Western Blot

USD :

569 USD

alt names :

6Ckine, 6CkineSmall-inducible cytokine A21, Beta-chemokine exodus-2, chemokine (C-C motif) ligand 21, CKb9, exodus-2, member 21, SCYA21, SCYA21MGC34555, secondary lymphoid tissue chemokine, SLC, SLCSecondary lymphoid-tissue chemokine, TCA-4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage