product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human GPR15 Antibody
catalog :
MAB3654
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
367902
reactivity :
human
application :
flow cytometry
more info or order :
R&D Systems product webpage
citations: 10
Reference
Fern xe1 ndez Ruiz J, Ochoa Gonz xe1 lez F, Zapata Z xfa xf1 iga M, Mondragon Mar xed n E, Lara Ram xed rez E, Ru xed z Carrillo J, et al. GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to the synovium. J Leukoc Biol. 2022;112:1209-1221 pubmed publisher
Bauer M, Fink B, Seyfarth H, Wirtz H, Frille A. Tobacco-smoking induced GPR15-expressing T cells in blood do not indicate pulmonary damage. BMC Pulm Med. 2017;17:159 pubmed publisher
Seong Y, Lazarus N, Sutherland L, Habtezion A, Abramson T, He X, et al. Trafficking receptor signatures define blood plasmablasts responding to tissue-specific immune challenge. JCI Insight. 2017;2:e90233 pubmed publisher
Wetzel K, Yi Y, Elliott S, Romero D, Jacquelin B, Hahn B, et al. CXCR6-Mediated Simian Immunodeficiency Virus SIVagmSab Entry into Sabaeus African Green Monkey Lymphocytes Implicates Widespread Use of Non-CCR5 Pathways in Natural Host Infections. J Virol. 2017;91: pubmed publisher
Fischer A, Zundler S, Atreya R, Rath T, Voskens C, Hirschmann S, et al. Differential effects of α4β7 and GPR15 on homing of effector and regulatory T cells from patients with UC to the inflamed gut in vivo. Gut. 2016;65:1642-64 pubmed publisher
Nguyen L, Pan J, Dinh T, Hadeiba H, O Hara E, Ebtikar A, et al. Role and species-specific expression of colon T cell homing receptor GPR15 in colitis. Nat Immunol. 2015;16:207-213 pubmed publisher
Cartwright A, Schmutz C, Askari A, Kuiper J, Middleton J. Orphan receptor GPR15/BOB is up-regulated in rheumatoid arthritis. Cytokine. 2014;67:53-9 pubmed publisher
Okamoto Y, Bernstein J, Shikano S. Role of C-terminal membrane-proximal basic residues in cell surface trafficking of HIV coreceptor GPR15 protein. J Biol Chem. 2013;288:9189-99 pubmed publisher
Kiene M, Marzi A, Urbanczyk A, Bertram S, Fisch T, Nehlmeier I, et al. The role of the alternative coreceptor GPR15 in SIV tropism for human cells. Virology. 2012;433:73-84 pubmed publisher
Okamoto Y, Shikano S. Phosphorylation-dependent C-terminal binding of 14-3-3 proteins promotes cell surface expression of HIV co-receptor GPR15. J Biol Chem. 2011;286:7171-81 pubmed publisher
product information
master code :
MAB3654
SKU :
MAB3654
product name :
Human GPR15 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human GPR15 Antibody from R&D Systems is a mouse monoclonal antibody to GPR15. This antibody reacts with human. The Human GPR15 Antibody has been validated for the following applications: CyTof,Flow Cytometry,CyTOF-reported.
target :
GPR15
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
367902
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
NS0 mouse myeloma cell line transfected with human GPR15, Met1-Leu360, Accession # P49685
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Stains human GPR15-transfected cells but not irrelevant transfectants.
gene symbol :
GPR15
top caption :
Detection of GPR15 antibody in HEK293 Human Cell Line Transfected with human GRP15 and eGFP antibody by Flow Cytometry.
accessionNumbers :
P49685
applications :
CyTof,Flow Cytometry,CyTOF-reported
USD :
499 USD
alt names :
BOB, Brother of Bonzo, G protein-coupled receptor 15, G-protein coupled receptor 15, MGC126828, MGC126830
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.