Human CX3CL1/Fractalkine Chemokine Domain Antibody | R&D Systems MAB3651 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CX3CL1/Fractalkine Chemokine Domain Antibody

catalog :

MAB3651

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

81513

reactivity :

human

application :

western blot, immunohistochemistry

citations: 8

Reference
Liu W, Molnár M, Garnham C, Benav H, Rask Andersen H. Macrophages in the Human Cochlea: Saviors or Predators-A Study Using Super-Resolution Immunohistochemistry. Front Immunol. 2018;9:223 pubmed publisher
Suzuki F, Kubota T, Miyazaki Y, Ishikawa K, Ebisawa M, Hirohata S, et al. Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity. Arthritis Res Ther. 2012;14:R48 pubmed publisher
Huang Y, Su P, Liu G, Crow M, Chaukos D, Yan H, et al. Constitutive endocytosis of the chemokine CX3CL1 prevents its degradation by cell surface metalloproteases. J Biol Chem. 2009;284:29644-53 pubmed publisher
Hurst L, Bunning R, Couraud P, Romero I, Weksler B, Sharrack B, et al. Expression of ADAM-17, TIMP-3 and fractalkine in the human adult brain endothelial cell line, hCMEC/D3, following pro-inflammatory cytokine treatment. J Neuroimmunol. 2009;210:108-12 pubmed publisher
Marchesi F, Piemonti L, Fedele G, Destro A, Roncalli M, Albarello L, et al. The chemokine receptor CX3CR1 is involved in the neural tropism and malignant behavior of pancreatic ductal adenocarcinoma. Cancer Res. 2008;68:9060-9 pubmed publisher
Truman L, Ford C, Pasikowska M, Pound J, Wilkinson S, Dumitriu I, et al. CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis. Blood. 2008;112:5026-36 pubmed publisher
Popovic M, Laumonnier Y, Burysek L, Syrovets T, Simmet T. Thrombin-induced expression of endothelial CX3CL1 potentiates monocyte CCL2 production and transendothelial migration. J Leukoc Biol. 2008;84:215-23 pubmed publisher
Volger O, Fledderus J, Kisters N, Fontijn R, Moerland P, Kuiper J, et al. Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis. Am J Pathol. 2007;171:326-37 pubmed

product information

brand :

R&D Systems

master code :

MAB3651

SKU :

MAB3651-100

product name :

Human CX3CL1/Fractalkine Chemokine Domain Antibody

description :

The Human CX3CL1/Fractalkine Chemokine Domain Antibody from R&D Systems is a mouse monoclonal antibody to CX3CL1/Fractalkine. This antibody reacts with human. The Human CX3CL1/Fractalkine Chemokine Domain Antibody has been validated for the following applications: Western Blot, Immunohistochemistry.

target :

CX3CL1/Fractalkine

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

81513

conjugate :

Unconjugated

host :

Mouse

immunogen :

NS0 and E. coli -derived recombinant human CX3CL1/Fractalkine Chemokine Domain, Gln25-Arg339 (Ser199Asn), Accession # P78423

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human CX3CL1/Fractalkine Chemokine Domain in direct ELISAs and Western blots.

gene symbol :

CX3CL1

catalog number base :

MAB3651

accessionNumbers :

P78423

applications :

Western Blot, Immunohistochemistry

2020 USD :

339

2021 USD :

359 USD

alt names :

ABCD-3, C3Xkine, chemokine (C-X3-C motif) ligand 1, CX3C membrane-anchored chemokine, CXC3, CXC3C, FKN, fractalkine, Neurotactin, neurotactin), NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, NTTSmall-inducible cytokine D1, SCYD1C-X3-C motif chemokine 1, small inducible cytokine subfamily D (Cys-X3-Cys), member-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.