product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CX3CL1/Fractalkine Chemokine Domain Antibody
catalog :
MAB3651-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
81513
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 13
Reference
Lunardi F, Abbrescia D, Vedovelli L, Pezzuto F, Fortarezza F, Comacchio G, et al. Molecular Profiling of Tissue Samples with Chronic Rejection from Patients with Chronic Lung Allograft Dysfunction: A Pilot Study in Cystic Fibrosis Patients. Biomolecules. 2023;13: pubmed publisher
Liu W, Danckwardt Lilliestr xf6 m N, Schrott Fischer A, Glueckert R, Rask Andersen H. Distribution of Immune Cells Including Macrophages in the Human Cochlea. Front Neurol. 2021;12:781702 pubmed publisher
Ostuni M, Hermand P, Saindoy E, Guillou N, Guellec J, Coens A, et al. CX3CL1 homo-oligomerization drives cell-to-cell adherence. Sci Rep. 2020;10:9069 pubmed publisher
Liu W, Kämpfe Nordström C, Danckwardt Lillieström N, Rask Andersen H. Human Inner Ear Immune Activity: A Super-Resolution Immunohistochemistry Study. Front Neurol. 2019;10:728 pubmed publisher
Kämpfe Nordström C, Danckwardt Lillieström N, Laurell G, Liu W, Rask Andersen H. The Human Endolymphatic Sac and Inner Ear Immunity: Macrophage Interaction and Molecular Expression. Front Immunol. 2018;9:3181 pubmed publisher
Liu W, Molnár M, Garnham C, Benav H, Rask Andersen H. Macrophages in the Human Cochlea: Saviors or Predators-A Study Using Super-Resolution Immunohistochemistry. Front Immunol. 2018;9:223 pubmed publisher
Suzuki F, Kubota T, Miyazaki Y, Ishikawa K, Ebisawa M, Hirohata S, et al. Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity. Arthritis Res Ther. 2012;14:R48 pubmed publisher
Huang Y, Su P, Liu G, Crow M, Chaukos D, Yan H, et al. Constitutive endocytosis of the chemokine CX3CL1 prevents its degradation by cell surface metalloproteases. J Biol Chem. 2009;284:29644-53 pubmed publisher
Hurst L, Bunning R, Couraud P, Romero I, Weksler B, Sharrack B, et al. Expression of ADAM-17, TIMP-3 and fractalkine in the human adult brain endothelial cell line, hCMEC/D3, following pro-inflammatory cytokine treatment. J Neuroimmunol. 2009;210:108-12 pubmed publisher
Marchesi F, Piemonti L, Fedele G, Destro A, Roncalli M, Albarello L, et al. The chemokine receptor CX3CR1 is involved in the neural tropism and malignant behavior of pancreatic ductal adenocarcinoma. Cancer Res. 2008;68:9060-9 pubmed publisher
Truman L, Ford C, Pasikowska M, Pound J, Wilkinson S, Dumitriu I, et al. CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis. Blood. 2008;112:5026-36 pubmed publisher
Popovic M, Laumonnier Y, Burysek L, Syrovets T, Simmet T. Thrombin-induced expression of endothelial CX3CL1 potentiates monocyte CCL2 production and transendothelial migration. J Leukoc Biol. 2008;84:215-23 pubmed publisher
Volger O, Fledderus J, Kisters N, Fontijn R, Moerland P, Kuiper J, et al. Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis. Am J Pathol. 2007;171:326-37 pubmed
product information
master code :
MAB3651
SKU :
MAB3651-100
product name :
Human CX3CL1/Fractalkine Chemokine Domain Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human CX3CL1/Fractalkine Chemokine Domain Antibody from R&D Systems is a mouse monoclonal antibody to CX3CL1/Fractalkine. This antibody reacts with human. The Human CX3CL1/Fractalkine Chemokine Domain Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry.
target :
CX3CL1/Fractalkine
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
81513
conjugate :
Unconjugated
host :
Mouse
immunogen :
NS0 and E. coli -derived recombinant human CX3CL1/Fractalkine Chemokine Domain, Gln25-Arg339 (Ser199Asn), Accession # P78423
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human CX3CL1/Fractalkine Chemokine Domain in direct ELISAs and Western blots.
gene symbol :
CX3CL1
accessionNumbers :
P78423
applications :
Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry
USD :
469 USD
alt names :
ABCD-3, C3Xkine, chemokine (C-X3-C motif) ligand 1, CX3C membrane-anchored chemokine, CXC3, CXC3C, FKN, fractalkine, Neurotactin, neurotactin), NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, NTTSmall-inducible cytokine D1, SCYD1C-X3-C motif chemokine 1, small inducible cytokine subfamily D (Cys-X3-Cys), member-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.