Human CX3CL1/Fractalkine Chemokine Domain Antibody | R&D Systems MAB365 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CX3CL1/Fractalkine Chemokine Domain Antibody

catalog :

MAB365

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

51637

reactivity :

human

citations: 8

Reference
Babendreyer A, Molls L, Dreymueller D, Uhlig S, Ludwig A. Shear Stress Counteracts Endothelial CX3CL1 Induction and Monocytic Cell Adhesion. Mediators Inflamm. 2017;2017:1515389 pubmed publisher
Suzuki F, Kubota T, Miyazaki Y, Ishikawa K, Ebisawa M, Hirohata S, et al. Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity. Arthritis Res Ther. 2012;14:R48 pubmed publisher
Truman L, Ford C, Pasikowska M, Pound J, Wilkinson S, Dumitriu I, et al. CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis. Blood. 2008;112:5026-36 pubmed publisher
Dame T, Orenzoff B, Palmer L, Furie M. IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation. J Immunol. 2007;178:1172-9 pubmed
Faure V, Cerini C, Paul P, Berland Y, Dignat George F, Brunet P. The uremic solute p-cresol decreases leukocyte transendothelial migration in vitro. Int Immunol. 2006;18:1453-9 pubmed
Deiva K, Geeraerts T, Salim H, Leclerc P, Hery C, Hugel B, et al. Fractalkine reduces N-methyl-d-aspartate-induced calcium flux and apoptosis in human neurons through extracellular signal-regulated kinase activation. Eur J Neurosci. 2004;20:3222-32 pubmed
Chazaud B, Sonnet C, Lafuste P, Bassez G, Rimaniol A, Poron F, et al. Satellite cells attract monocytes and use macrophages as a support to escape apoptosis and enhance muscle growth. J Cell Biol. 2003;163:1133-43 pubmed
Lucas A, Chadwick N, Warren B, Jewell D, Gordon S, Powrie F, et al. The transmembrane form of the CX3CL1 chemokine fractalkine is expressed predominantly by epithelial cells in vivo. Am J Pathol. 2001;158:855-66 pubmed

product information

brand :

R&D Systems

master code :

MAB365

SKU :

MAB365-100

product name :

Human CX3CL1/Fractalkine Chemokine Domain Antibody

description :

The Human CX3CL1/Fractalkine Chemokine Domain Antibody from R&D Systems is a mouse monoclonal antibody to CX3CL1/Fractalkine. This antibody reacts with human. The Human CX3CL1/Fractalkine Chemokine Domain Antibody has been validated for the following applications: Intracellular Staining by Flow Cytometry, CyTOF-ready.

target :

CX3CL1/Fractalkine

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

51637

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human CX3CL1/Fractalkine Chemokine Domain, Gln25-Arg339 (Ser199Asn) (predicted), Accession # P78423

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CX3CL1/Fractalkine Chemokine Domain in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse CX3CL1 or recombinant rat CX3CL1 is observed.

gene symbol :

CX3CL1

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB365

accessionNumbers :

P78423

applications :

Intracellular Staining by Flow Cytometry, CyTOF-ready

2020 USD :

339

2021 USD :

359 USD

alt names :

ABCD-3, C3Xkine, chemokine (C-X3-C motif) ligand 1, CX3C membrane-anchored chemokine, CXC3, CXC3C, FKN, fractalkine, Neurotactin, neurotactin), NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, NTTSmall-inducible cytokine D1, SCYD1C-X3-C motif chemokine 1, small inducible cytokine subfamily D (Cys-X3-Cys), member-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.