Human CCL17/TARC Antibody | R&D Systems MAB364-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCL17/TARC Antibody

catalog :

MAB364-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

54026

reactivity :

human

application :

ELISA, neutralization

more info or order :

R&D Systems product webpage

citations: 11

Reference
Magnotti E, Chan L, Zhu Q, Marasco W. A high-throughput chemotaxis detection method for CCR4+ T cell migration inhibition using image cytometry. J Immunol Methods. 2020;479:112747 pubmed publisher
Wang Y, Weng X, Wang L, Hao M, Li Y, Hou L, et al. HIC1 deletion promotes breast cancer progression by activating tumor cell/fibroblast crosstalk. J Clin Invest. 2018;128:5235-5250 pubmed publisher
He W, Bai G, Zhou H, Wei N, White N, Lauer J, et al. CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase. Nature. 2015;526:710-4 pubmed publisher
Paantjens A, van de Graaf E, Kwakkel van Erp J, Hoefnagel T, van Kessel D, van den Bosch J, et al. Lung transplantation affects expression of the chemokine receptor type 4 on specific T cell subsets. Clin Exp Immunol. 2011;166:103-9 pubmed publisher
Mizukami Y, Kono K, Kawaguchi Y, Akaike H, Kamimura K, Sugai H, et al. CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer. Int J Cancer. 2008;122:2286-93 pubmed publisher
Haas J, Schopp L, Storch Hagenlocher B, Fritzsching B, Jacobi C, Milkova L, et al. Specific recruitment of regulatory T cells into the CSF in lymphomatous and carcinomatous meningitis. Blood. 2008;111:761-6 pubmed
Liu L, Bates M, Jarjour N, Busse W, Bertics P, Kelly E. Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha. J Immunol. 2007;179:4840-8 pubmed
Vestergaard C, Johansen C, Christensen U, Just H, Hohwy T, Deleuran M. TARC augments TNF-alpha-induced CTACK production in keratinocytes. Exp Dermatol. 2004;13:551-7 pubmed
Curiel T, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med. 2004;10:942-9 pubmed
Liu L, Jarjour N, Busse W, Kelly E. Enhanced generation of helper T type 1 and 2 chemokines in allergen-induced asthma. Am J Respir Crit Care Med. 2004;169:1118-24 pubmed
Thompson S, Luyrink L, Graham T, Tsoras M, Ryan M, Passo M, et al. Chemokine receptor CCR4 on CD4+ T cells in juvenile rheumatoid arthritis synovial fluid defines a subset of cells with increased IL-4:IFN-gamma mRNA ratios. J Immunol. 2001;166:6899-906 pubmed

product information

master code :

MAB364

SKU :

MAB364-100

product name :

Human CCL17/TARC Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human CCL17/TARC Antibody from R&D Systems is a mouse monoclonal antibody to CCL17/TARC. This antibody reacts with human. The Human CCL17/TARC Antibody has been validated for the following applications: Bioassay,ELISA Development,Neutralization,ELISA Capture (Matched Antibody Pair).

target :

CCL17/TARC

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

54026

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CCL17/TARC, Ala24-Ser94, Accession # Q92583.1

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CCL17/TARC in ELISAs. Does not cross-react with recombinant human (rh) CCL2, 3, 4, 5, 7, 8, 11, 13, 16, 18, 19, 20, 21, 22, 23, 24, 25, rmCCL2, 3, 4, 5, 7, 9/10/MIP-1 gamma , 11, 12, 21, 22, 25, or rrCCL20.

gene symbol :

CCL17

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Chemotaxis Induced by CCL17/TARC and Neutralization by Human CCL17/TARC Antibody.

accessionNumbers :

Q92583.1

applications :

Bioassay,ELISA Development,Neutralization,ELISA Capture (Matched Antibody Pair)

USD :

479 USD

alt names :

ABCD-2, CC chemokine TARC, C-C motif chemokine 17, chemokine (C-C motif) ligand 17, MGC138273, SCYA17, SCYA17MGC138271, small inducible cytokine subfamily A (Cys-Cys), member 17, Small-inducible cytokine A17, T cell-directed CC chemokine, TARC, TARCA-152E5.3, Thymus and activation-regulated chemokine

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage