product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse IL-33 Antibody
catalog :
MAB3626
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
396118
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 27
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 4i
Liu J, Wang C, Cheng T, Rixiati Y, Ji C, Deng M, et al. Circadian Clock Disruption Suppresses PDL1+ Intraepithelial B Cells in Experimental Colitis and Colitis-Associated Colorectal Cancer. Cell Mol Gastroenterol Hepatol. 2021;12:251-276 pubmed publisher
Uapinyoying P, Hogarth M, Battacharya S, M xe1 zala D, Panchapakesan K, B xf6 nnemann C, et al. Single-cell transcriptomic analysis of the identity and function of fibro/adipogenic progenitors in healthy and dystrophic muscle. iScience. 2023;26:107479 pubmed publisher
Kiaf B, Bode K, Schuster C, Kissler S. Gata3 is detrimental to regulatory T cell function in autoimmune diabetes. bioRxiv. 2023;: pubmed publisher
Jayawardena D, Priyamvada S, Kageyama T, White Z, Kumar A, Griggs T, et al. Loss of SLC26A3 Results in Colonic Mucosal Immune Dysregulation via Epithelial-Immune Cell Crosstalk. Cell Mol Gastroenterol Hepatol. 2023;15:903-919 pubmed publisher
Sharma D, Bisen S, Kaur G, Van Buren E, Rao G, Singh N. IL-33 enhances Jagged1 mediated NOTCH1 intracellular domain (NICD) deubiquitination and pathological angiogenesis in proliferative retinopathy. Commun Biol. 2022;5:479 pubmed publisher
Patial S, Lewis B, Vo T, Choudhary I, Paudel K, Mao Y, et al. Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs. Sci Rep. 2021;11:15465 pubmed publisher
Toyama S, Moniaga C, Nakae S, Kurosawa M, Ogawa H, Tominaga M, et al. Regulatory T Cells Exhibit Interleukin-33-Dependent Migratory Behavior during Skin Barrier Disruption. Int J Mol Sci. 2021;22: pubmed publisher
Kubo F, Ariestanti D, Oki S, Fukuzawa T, Demizu R, Sato T, et al. Loss of the adhesion G-protein coupled receptor ADGRF5 in mice induces airway inflammation and the expression of CCL2 in lung endothelial cells. Respir Res. 2019;20:11 pubmed publisher
He Z, Chen L, Furtado G, Lira S. Interleukin 33 regulates gene expression in intestinal epithelial cells independently of its nuclear localization. Cytokine. 2018;111:146-153 pubmed publisher
Barbour M, Wood R, Hridi S, Wilson C, McKay G, Bushell T, et al. The therapeutic effect of anti-CD52 treatment in murine experimental autoimmune encephalomyelitis is associated with altered IL-33 and ST2 expression levels. J Neuroimmunol. 2018;318:87-96 pubmed publisher
Kang H, Yang K, Xiao L, Guo L, Guo C, Yan Y, et al. Osteoblast Hypoxia-Inducible Factor-1? Pathway Activation Restrains Osteoclastogenesis via the Interleukin-33-MicroRNA-34a-Notch1 Pathway. Front Immunol. 2017;8:1312 pubmed publisher
Qi F, Bai S, Wang D, Xu L, Hu H, Zeng S, et al. Macrophages produce IL-33 by activating MAPK signaling pathway during RSV infection. Mol Immunol. 2017;87:284-292 pubmed publisher
Liu T, Kanaoka Y, Barrett N, Feng C, Garofalo D, Lai J, et al. Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway. J Immunol. 2015;195:3537-45 pubmed publisher
Wu J, Carlock C, Zhou C, Nakae S, Hicks J, Adams H, et al. IL-33 is required for disposal of unnecessary cells during ovarian atresia through regulation of autophagy and macrophage migration. J Immunol. 2015;194:2140-7 pubmed publisher
Chen F, Wu W, Millman A, Craft J, Chen E, Patel N, et al. Neutrophils prime a long-lived effector macrophage phenotype that mediates accelerated helminth expulsion. Nat Immunol. 2014;15:938-46 pubmed publisher
Schiering C, Krausgruber T, Chomka A, Fröhlich A, Adelmann K, Wohlfert E, et al. The alarmin IL-33 promotes regulatory T-cell function in the intestine. Nature. 2014;513:564-568 pubmed publisher
Carlock C, Wu J, Zhou C, Tatum K, Adams H, TAN F, et al. Unique temporal and spatial expression patterns of IL-33 in ovaries during ovulation and estrous cycle are associated with ovarian tissue homeostasis. J Immunol. 2014;193:161-9 pubmed publisher
Huang J, Tsai Y, Chang Y, Wu J, Hung J, Lin K, et al. α-Galactosylceramide but not phenyl-glycolipids induced NKT cell anergy and IL-33-mediated myeloid-derived suppressor cell accumulation via upregulation of egr2/3. J Immunol. 2014;192:1972-81 pubmed publisher
Guabiraba R, Besnard A, Menezes G, Secher T, Jabir M, Amaral S, et al. IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice. Mucosal Immunol. 2014;7:1079-93 pubmed publisher
Mizutani N, Nabe T, Yoshino S. Interleukin-33 and alveolar macrophages contribute to the mechanisms underlying the exacerbation of IgE-mediated airway inflammation and remodelling in mice. Immunology. 2013;139:205-18 pubmed publisher
Juncadella I, Kadl A, Sharma A, Shim Y, Hochreiter Hufford A, Borish L, et al. Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation. Nature. 2013;493:547-51 pubmed publisher
Kaieda S, Wang J, Shnayder R, Fishgal N, Hei H, Lee R, et al. Interleukin-33 primes mast cells for activation by IgG immune complexes. PLoS ONE. 2012;7:e47252 pubmed publisher
Hsu C, Bryce P. Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway. J Immunol. 2012;189:3421-9 pubmed
Jiang H, Milovanovic M, Allan D, Niedbala W, Besnard A, Fukada S, et al. IL-33 attenuates EAE by suppressing IL-17 and IFN-? production and inducing alternatively activated macrophages. Eur J Immunol. 2012;42:1804-14 pubmed publisher
Yasuoka S, Kawanokuchi J, Parajuli B, Jin S, Doi Y, Noda M, et al. Production and functions of IL-33 in the central nervous system. Brain Res. 2011;1385:8-17 pubmed publisher
Hsu C, Neilsen C, Bryce P. IL-33 is produced by mast cells and regulates IgE-dependent inflammation. PLoS ONE. 2010;5:e11944 pubmed publisher
Hudson C, Christophi G, Gruber R, Wilmore J, Lawrence D, Massa P. Induction of IL-33 expression and activity in central nervous system glia. J Leukoc Biol. 2008;84:631-43 pubmed publisher
product information
master code :
MAB3626
SKU :
MAB3626
product name :
Mouse IL-33 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse IL-33 Antibody from R&D Systems is a rat monoclonal antibody to IL-33. This antibody reacts with mouse,transgenic mouse. The Mouse IL-33 Antibody has been validated for the following applications: ELISA Development,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Immunocytochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready.
target :
IL-33
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
396118
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse IL-33, Ser109-Ile266, Accession # Q8BVZ5
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse,Transgenic Mouse
specificity :
Detects mouse IL-33 in direct ELISAs.
gene symbol :
IL33
top caption :
Detection of Mouse IL-33 antibody by Western Blot.
accessionNumbers :
Q8BVZ5
applications :
ELISA Development,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Immunocytochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready
USD :
479 USD
alt names :
C9orf26, C9orf26chromosome 9 open reading frame 26 (NF-HEV), DKFZp586H0523, DVS27, DVS27-related protein, IL1F11, IL-1F11, IL33, IL-33, interleukin 33, Interleukin-1 family member 11, interleukin-33, NFHEV, NF-HEV, NF-HEVNFEHEV, Nuclear factor from high endothelial venules, RP11-575C20.2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.