product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ChemR23 Antibody
catalog :
MAB362
quantity :
500 ug (also 25 ug)
price :
579 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
84939
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 8
Reference
Herová M, Schmid M, Gemperle C, Hersberger M. ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages. J Immunol. 2015;194:2330-7 pubmed publisher
Zhou J, Liao D, Zhang S, Cheng N, He H, Ye R. Chemerin C9 peptide induces receptor internalization through a clathrin-independent pathway. Acta Pharmacol Sin. 2014;35:653-63 pubmed publisher
Cash J, Bena S, Headland S, McArthur S, Brancaleone V, Perretti M. Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. EMBO Rep. 2013;14:999-1007 pubmed publisher
de Poorter C, Baertsoen K, Lannoy V, Parmentier M, Springael J. Consequences of ChemR23 heteromerization with the chemokine receptors CXCR4 and CCR7. PLoS ONE. 2013;8:e58075 pubmed publisher
Gao L, Faibish D, Fredman G, Herrera B, Chiang N, Serhan C, et al. Resolvin E1 and chemokine-like receptor 1 mediate bone preservation. J Immunol. 2013;190:689-94 pubmed publisher
Berg V, Sveinbjörnsson B, Bendiksen S, Brox J, Meknas K, Figenschau Y. Human articular chondrocytes express ChemR23 and chemerin; ChemR23 promotes inflammatory signalling upon binding the ligand chemerin(21-157). Arthritis Res Ther. 2010;12:R228 pubmed publisher
Skrzeczynska Moncznik J, Wawro K, Stefanska A, Oleszycka E, Kulig P, Zabel B, et al. Potential role of chemerin in recruitment of plasmacytoid dendritic cells to diseased skin. Biochem Biophys Res Commun. 2009;380:323-7 pubmed publisher
Mårtensson U, Fenyo E, Olde B, Owman C. Characterization of the human chemerin receptor--ChemR23/CMKLR1--as co-receptor for human and simian immunodeficiency virus infection, and identification of virus-binding receptor domains. Virology. 2006;355:6-17 pubmed
product information
master code :
MAB362
SKU :
MAB362
product name :
Human ChemR23 Antibody
unit size :
500 ug (also 25 ug)
description :
The Human ChemR23 Antibody from R&D Systems is a mouse monoclonal antibody to ChemR23/CMKLR1. This antibody reacts with human,mouse. The Human ChemR23 Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry,CyTOF-ready.
target :
ChemR23
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
84939
conjugate :
Unconjugated
host :
Mouse
immunogen :
NS0 mouse myeloma cell line transfected with human ChemR23, Met1-Leu371, Accession # NP_004063
isotype :
IgG3
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human ChemR23. Stains human ChemR23-transfected cells but not irrelevant transfectants.
gene symbol :
CMKLR1
top caption :
Detection of ChemR23/CMKLR1 by Immunocytochemistry/ Immunofluorescence
accessionNumbers :
NP_004063
applications :
Flow Cytometry,Immunocytochemistry,CyTOF-ready
USD :
579 USD
alt names :
CHEMERINR, chemokine receptor-like 1, chemokine-like receptor 1, CHEMR23, cmklr1, Dez, Gpcr27, G-protein coupled receptor ChemR23, G-protein coupled receptor DEZ, MGC126105, MGC126106, orphan G-protein coupled receptor, Dez
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.