Human CCL20/MIP-3 alpha Antibody | R&D Systems MAB360-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCL20/MIP-3 alpha Antibody

catalog :

MAB360-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

67310

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 45

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:100; loading ...; fig 2d	Choi Y, Kim Y, Oh S, Suh K, Kim Y, Lee G, et al. Senescent Tumor Cells Build a Cytokine Shield in Colorectal Cancer. Adv Sci (Weinh). 2021;8:2002497 pubmed publisher
	Elabi O, Espa E, Skovg xe5 rd K, Fanni S, Cenci M. Ropinirole Cotreatment Prevents Perivascular Glial Recruitment in a Rat Model of L-DOPA-Induced Dyskinesia. Cells. 2023;12: pubmed publisher
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	Kano H, Izumi K, Hiratsuka K, Toriumi R, Nakagawa R, Aoyama S, et al. Suppression of androgen receptor signaling induces prostate cancer migration via activation of the CCL20-CCR6 axis. Cancer Sci. 2023;114:1479-1490 pubmed publisher
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	Morel C, Christophe A, Maguin Gat xe9 K, Paoli J, Turner J, Schroeder H, et al. Head-to-Head Study of Developmental Neurotoxicity and Resultant Phenotype in Rats: α-Hexabromocyclododecane versus Valproic Acid, a Recognized Model of Reference for Autism Spectrum Disorders. Toxics. 2022;10: pubmed publisher
	Esteves P, Allard B, Celle A, Dupin I, Maurat E, Ousova O, et al. Asthmatic bronchial smooth muscle increases rhinovirus replication within the bronchial epithelium. Cell Rep. 2022;38:110571 pubmed publisher
	Liu X, Liu B, Yang Q, Zhou X, Tang S. Microglial ablation does not affect opioid-induced hyperalgesia in rodents. Pain. 2022;163:508-517 pubmed publisher
	Xia L, Liu L, Cai Y, Zhang Y, Tong F, Wang Q, et al. Inhibition of Gasdermin D-Mediated Pyroptosis Attenuates the Severity of Seizures and Astroglial Damage in Kainic Acid-Induced Epileptic Mice. Front Pharmacol. 2021;12:751644 pubmed publisher
	Liu Y, Fu H, Wu Y, Nie B, Liu F, Wang T, et al. Elamipretide (SS-31) Improves Functional Connectivity in Hippocampus and Other Related Regions Following Prolonged Neuroinflammation Induced by Lipopolysaccharide in Aged Rats. Front Aging Neurosci. 2021;13:600484 pubmed publisher
	Wang Y, Lyu Z, Qin Y, Wang X, Sun L, Zhang Y, et al. FOXO1 promotes tumor progression by increased M2 macrophage infiltration in esophageal squamous cell carcinoma. Theranostics. 2020;10:11535-11548 pubmed publisher
	Li A, Zhang N, Zhao Z, Chen Y, Zhang L. Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8. Oncol Lett. 2020;20:1535-1544 pubmed publisher
	Mike J, Pathipati P, Sheldon R, Ferriero D. Changes in arginase isoforms in a murine model of neonatal brain hypoxia-ischemia. Pediatr Res. 2021;89:830-837 pubmed publisher
	Nayrac M, Requena M, Loiseau C, Cazabat M, Suc B, Carrere N, et al. Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals. Mucosal Immunol. 2021;14:219-228 pubmed publisher
	Huang A, Woo J, Sardar D, Lozzi B, Bosquez Huerta N, Lin C, et al. Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities. Neuron. 2020;106:992-1008.e9 pubmed publisher
	Patel B, McNamara M, Pesquera Colom L, Kozik E, Okuzonu J, Hashemi N, et al. Recovery of Encapsulated Adult Neural Progenitor Cells from Microfluidic-Spun Hydrogel Fibers Enhances Proliferation and Neuronal Differentiation. ACS Omega. 2020;5:7910-7918 pubmed publisher
	Jacob F, Salinas R, Zhang D, Nguyen P, Schnoll J, Wong S, et al. A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity. Cell. 2020;180:188-204.e22 pubmed publisher
	Choi S, Han H, Beitz A, Lee J. Spinal Interleukin-1β Inhibits Astrocyte Cytochrome P450c17 Expression Which Controls the Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain. Front Mol Neurosci. 2019;12:153 pubmed publisher
	Govier Cole A, Wood R, Fletcher J, Gonsalvez D, Merlo D, Cate H, et al. Inhibiting Bone Morphogenetic Protein 4 Type I Receptor Signaling Promotes Remyelination by Potentiating Oligodendrocyte Differentiation. Eneuro. 2019;6: pubmed publisher
	He Q, Gao Y, Wang T, Zhou L, Zhou W, Yuan Z. Deficiency of Yes-Associated Protein Induces Cataract in Mice. Aging Dis. 2019;10:293-306 pubmed publisher
	Weise S, Villarreal A, Heidrich S, Dehghanian F, Schachtrup C, Nestel S, et al. TGFβ-Signaling and FOXG1-Expression Are a Hallmark of Astrocyte Lineage Diversity in the Murine Ventral and Dorsal Forebrain. Front Cell Neurosci. 2018;12:448 pubmed publisher
	Goulao M, Ghosh B, Urban M, Sahu M, Mercogliano C, Charsar B, et al. Astrocyte progenitor transplantation promotes regeneration of bulbospinal respiratory axons, recovery of diaphragm function, and a reduced macrophage response following cervical spinal cord injury. Glia. 2019;67:452-466 pubmed publisher
	Won S, Minnella A, Wu L, Eun C, Rome E, Herson P, et al. Cofilin-actin rod formation in neuronal processes after brain ischemia. PLoS ONE. 2018;13:e0198709 pubmed publisher
	Vay S, Flitsch L, Rabenstein M, Rogall R, Blaschke S, Kleinhaus J, et al. The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo. J Neuroinflammation. 2018;15:226 pubmed publisher
	Sandquist E, Essner J, Sakaguchi D. Xenotransplantation of adult hippocampal neural progenitors into the developing zebrafish for assessment of stem cell plasticity. PLoS ONE. 2018;13:e0198025 pubmed publisher
	Jayaraman S, Doucet M, Kominsky S. CITED2 attenuates macrophage recruitment concordant with the downregulation of CCL20 in breast cancer cells. Oncol Lett. 2018;15:871-878 pubmed publisher
	Soto B, Gallastegi Mozos T, Rodriguez C, Martinez Gonzalez J, Escudero J, Vila L, et al. Circulating CCL20 as a New Biomarker of Abdominal Aortic Aneurysm. Sci Rep. 2017;7:17331 pubmed publisher
	Loiseau C, Requena M, Mavigner M, Cazabat M, Carrere N, Suc B, et al. CCR6(-) regulatory T cells blunt the restoration of gut Th17 cells along the CCR6-CCL20 axis in treated HIV-1-infected individuals. Mucosal Immunol. 2016;9:1137-50 pubmed publisher
	Ikeda S, Kitadate A, Ito M, Abe F, Nara M, Watanabe A, et al. Disruption of CCL20-CCR6 interaction inhibits metastasis of advanced cutaneous T-cell lymphoma. Oncotarget. 2016;7:13563-74 pubmed publisher
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	Baumforth K, Birgersdotter A, Reynolds G, Wei W, Kapatai G, Flavell J, et al. Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates Up-regulation of CCL20 and the migration of regulatory T cells. Am J Pathol. 2008;173:195-204 pubmed publisher
	Huang S, Chen C, Schatz F, Rahman M, Abrahams V, Lockwood C. Pre-eclampsia is associated with dendritic cell recruitment into the uterine decidua. J Pathol. 2008;214:328-36 pubmed
	Pi S, Kim S, Min K, Lee H, Chang H, Kang K, et al. Substance P regulates macrophage inflammatory protein 3alpha/chemokine C-C ligand 20 (CCL20) with heme oxygenase-1 in human periodontal ligament cells. Clin Exp Immunol. 2007;150:567-75 pubmed
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product information

master code :

MAB360

SKU :

MAB360-100

product name :

Human CCL20/MIP-3 alpha Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human CCL20/MIP-3 alpha Antibody from R&D Systems is a mouse monoclonal antibody to CCL20/MIP-3 alpha. This antibody reacts with human. The Human CCL20/MIP-3 alpha Antibody has been validated for the following applications: Western Blot,Antibody Array Development,Bioassay,ELISA Development,Neutralization,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA Capture (Matched Antibody Pair).

target :

CCL20/MIP-3 alpha

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

67310

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CCL20/MIP-3 alpha , Ala27-Met96 (Asn95Asp), Accession # P78556.1

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CCL20/MIP-3 alpha in ELISAs and Western blots. In ELISAs, no cross-reactivity with recombinant human (rh) CCL19, rhCXCL1, rhCCL16, rhCCL11, recombinant mouse CCL20/MIP-3 alpha , or recombinant rat CCL20/MIP-3 alpha is observed.

gene symbol :

CCL20

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Recombinant Human CCL20/MIP-3a antibody by Western Blot.

accessionNumbers :

P78556.1

applications :

Antibody Array Development,Bioassay,ELISA Development,Neutralization,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Western Blot,ELISA Capture (Matched Antibody Pair)

USD :

469 USD

alt names :

beta chemokine exodus-1, Beta-chemokine exodus-1, CC chemokine LARC, C-C motif chemokine 20, chemokine (C-C motif) ligand 20, CKb4, exodus-1, LARC, LARCLiver and activation-regulated chemokine, MIP3 alpha, MIP-3 alpha, MIP-3a, MIP-3-alpha, MIP3AMacrophage inflammatory protein 3 alpha, SCYA20Small-inducible cytokine A20, small inducible cytokine subfamily A (Cys-Cys), member 20, ST38

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage