Human/Mouse/Rat RIPK1/RIP1 Antibody | R&D Systems MAB3585 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat RIPK1/RIP1 Antibody

catalog :

MAB3585

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

334640

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 16

Reference
Liu C, Cao Y, Wang H, Zhao L, Chen Y, Zhong K, et al. Necrostatin-1 decreases necroptosis and inflammatory markers after intraventricular hemorrhage in mice. Neural Regen Res. 2022;17:2710-2716 pubmed publisher
Yu F, Tian W, Dong J. Anagliptin prevents lipopolysaccharide (LPS)- induced inflammation and activation of macrophages. Int Immunopharmacol. 2022;104:108514 pubmed publisher
Shang P, Stepicheva N, Liu H, Chowdhury O, Franks J, Sun M, et al. A Novel Method of Mouse RPE Explant Culture and Effective Introduction of Transgenes Using Adenoviral Transduction for In Vitro Studies in AMD. Int J Mol Sci. 2021;22: pubmed publisher
Shang P, Stepicheva N, Teel K, McCauley A, Fitting C, Hose S, et al. βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells. Commun Biol. 2021;4:850 pubmed publisher
Cheng R, Liu X, Wang Z, Tang K. ABT‑737, a Bcl‑2 family inhibitor, has a synergistic effect with apoptosis by inducing urothelial carcinoma cell necroptosis. Mol Med Rep. 2021;23: pubmed publisher
Baidya R, Gautheron J, Crawford D, Wang H, Bridle K. Inhibition of MLKL Attenuates Necroptotic Cell Death in a Murine Cell Model of Ischaemia Injury. J Clin Med. 2021;10: pubmed publisher
Sun C, Chesnokov V, Larson G, Itakura K. Glucosamine Enhances TRAIL-Induced Apoptosis in the Prostate Cancer Cell Line DU145. Medicines (Basel). 2019;6: pubmed publisher
Gennaro V, Wedegaertner H, McMahon S. Interaction between the BAG1S isoform and HSP70 mediates the stability of anti-apoptotic proteins and the survival of osteosarcoma cells expressing oncogenic MYC. BMC Cancer. 2019;19:258 pubmed publisher
Luz N, Khouri R, Van Weyenbergh J, Zanette D, Fiuza P, Noronha A, et al. Leishmania braziliensis Subverts Necroptosis by Modulating RIPK3 Expression. Front Microbiol. 2018;9:2283 pubmed publisher
Chen J, Wang S, Fu R, Zhou M, Zhang T, Pan W, et al. RIP3 dependent NLRP3 inflammasome activation is implicated in acute lung injury in mice. J Transl Med. 2018;16:233 pubmed publisher
Chen R, Xu J, She Y, Jiang T, Zhou S, Shi H, et al. Necrostatin-1 protects C2C12 myotubes from CoCl2-induced hypoxia. Int J Mol Med. 2018;41:2565-2572 pubmed publisher
Ito K, Eguchi Y, Imagawa Y, Akai S, Mochizuki H, Tsujimoto Y. MPP+ induces necrostatin-1- and ferrostatin-1-sensitive necrotic death of neuronal SH-SY5Y cells. Cell Death Discov. 2017;3:17013 pubmed publisher
Bullova P, Cougnoux A, Abunimer L, Kopacek J, Pastorekova S, Pacak K. Hypoxia potentiates the cytotoxic effect of piperlongumine in pheochromocytoma models. Oncotarget. 2016;7:40531-40545 pubmed publisher
Oshima R, Hasegawa T, Tamai K, Sugeno N, Yoshida S, Kobayashi J, et al. ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways. Sci Rep. 2016;6:24997 pubmed publisher
Xu J, Wu F, Tian D, Wang J, Zheng Z, Xia N. Open reading frame 3 of genotype 1 hepatitis E virus inhibits nuclear factor-?appa B signaling induced by tumor necrosis factor-? in human A549 lung epithelial cells. PLoS ONE. 2014;9:e100787 pubmed publisher
Ikner A, Ashkenazi A. TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8. J Biol Chem. 2011;286:21546-54 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB3585

SKU :

MAB3585

product name :

Human/Mouse/Rat RIPK1/RIP1 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse/Rat RIPK1/RIP1 Antibody from R&D Systems is a mouse monoclonal antibody to RIPK1/RIP1. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat RIPK1/RIP1 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Simple Western,Immunocytochemistry,Knockout Validated.

target :

RIPK1/RIP1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

334640

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.5 ug/mL, Simple Western 10 ug/mL, Immunocytochemistry 8-25 ug/mL, Knockout Validated

host :

Mouse

immunogen :

E. coli -derived recombinant human RIPK1/RIP1, Met1-Asn671, Accession # Q13546

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects human, mouse and rat RIPK1/RIP1 in Western blots.

gene symbol :

RIPK1

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human/Mouse/Rat RIPK1/RIP1 antibody by Western Blot.

accessionNumbers :

Q13546

applications :

Simple Western,Immunocytochemistry,Knockout Validated,Flow Cytometry,Western Blot

USD :

479 USD

alt names :

Cell death protein RIP, EC 2.7.11.1, receptor (TNFRSF)-interacting serine-threonine kinase 1, receptor interacting protein, Receptor-interacting protein 1, receptor-interacting serine/threonine-protein kinase 1, RIP, RIP1, RIP-1, Rip1 kinase, RIPFLJ39204, Serine/threonine-protein kinase RIP

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage