product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human HGFR/c-MET Antibody
catalog :
MAB3582
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
95106
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 14
Reference
Kang C, Kim Y, Lee D, Choi S, Lee H, Park C. c-Met-Specific Chimeric Antigen Receptor T Cells Demonstrate Anti-Tumor Effect in c-Met Positive Gastric Cancer. Cancers (Basel). 2021;13: pubmed publisher
Wurster K, Costanza M, Kreher S, Glaser S, Lamprecht B, Schleussner N, et al. Aberrant Expression of and Cell Death Induction by Engagement of the MHC-II Chaperone CD74 in Anaplastic Large Cell Lymphoma (ALCL). Cancers (Basel). 2021;13: pubmed publisher
Di Franco S, Bianca P, Sardina D, Turdo A, Gaggianesi M, Veschi V, et al. Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery. Nat Commun. 2021;12:5006 pubmed publisher
De Bacco F, Orzan F, Erriquez J, Casanova E, Barault L, Albano R, et al. ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma. Cell Rep. 2021;36:109455 pubmed publisher
Khan T, Seddon A, Dalgleish A, Khelwatty S, Ioannou N, Mudan S, et al. Synergistic activity of agents targeting growth factor receptors, CDKs and downstream signaling molecules in a panel of pancreatic cancer cell lines and the identification of antagonistic combinations: Implications for future clinical trials in pancr. Oncol Rep. 2020;44:2581-2594 pubmed publisher
Stringer B, Day B, D Souza R, Jamieson P, Ensbey K, Bruce Z, et al. A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma. Sci Rep. 2019;9:4902 pubmed publisher
Breunig C, Erdem N, Bott A, Greiwe J, Reinz E, Bernhardt S, et al. TGFβ1 regulates HGF-induced cell migration and hepatocyte growth factor receptor MET expression via C-ets-1 and miR-128-3p in basal-like breast cancer. Mol Oncol. 2018;12:1447-1463 pubmed publisher
Zhang W, Duan R, Zhang J, Cheung W, Gao X, Zhang R, et al. H1/pHGFK1 nanoparticles exert anti-tumoural and radiosensitising effects by inhibition of MET in glioblastoma. Br J Cancer. 2018;118:522-533 pubmed publisher
Montagne R, Berbon M, Doublet L, Debreuck N, Baranzelli A, Drobecq H, et al. Necrosis- and apoptosis-related Met cleavages have divergent functional consequences. Cell Death Dis. 2015;6:e1769 pubmed publisher
Vogel S, Börger V, Peters C, Förster M, Liebfried P, Metzger K, et al. Necrotic cell-derived high mobility group box 1 attracts antigen-presenting cells but inhibits hepatocyte growth factor-mediated tropism of mesenchymal stem cells for apoptotic cell death. Cell Death Differ. 2015;22:1219-30 pubmed publisher
Carbonell W, Delay M, Jahangiri A, Park C, Aghi M. ?1 integrin targeting potentiates antiangiogenic therapy and inhibits the growth of bevacizumab-resistant glioblastoma. Cancer Res. 2013;73:3145-54 pubmed publisher
Xu L, Hausmann M, Dietmaier W, Kellermeier S, Pesch T, Stieber Gunckel M, et al. Expression of growth factor receptors and targeting of EGFR in cholangiocarcinoma cell lines. BMC Cancer. 2010;10:302 pubmed publisher
Foveau B, Ancot F, Leroy C, Petrelli A, Reiss K, Vingtdeux V, et al. Down-regulation of the met receptor tyrosine kinase by presenilin-dependent regulated intramembrane proteolysis. Mol Biol Cell. 2009;20:2495-507 pubmed publisher
Riccioni R, Senese M, Diverio D, Riti V, Mariani G, Boe A, et al. Resistance of acute myeloid leukemic cells to the triterpenoid CDDO-Imidazolide is associated with low caspase-8 and FADD levels. Leuk Res. 2008;32:1244-58 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB3582
SKU :
MAB3582
product name :
Human HGFR/c-MET Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human HGFR/c-MET Antibody from R&D Systems is a mouse monoclonal antibody to HGFR/c-MET. This antibody reacts with human. The Human HGFR/c-MET Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry,CyTOF-ready.
target :
HGFR/c-MET
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
95106
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Flow Cytometry 2.5 ug/10^6 cells, CyTOF-ready
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human HGF R/c-MET, Glu25-Thr932, Accession # P08581
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human HGF R/c-MET.
gene symbol :
MET
top caption :
Detection of HGF R/c-MET antibody in MDA-MB-231 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
P08581
applications :
CyTOF-ready,Flow Cytometry,Immunocytochemistry
USD :
489 USD
alt names :
AUTS9, c-Met, cMET, EC 2.7.10, EC 2.7.10.1, hepatocyte growth factor receptor, HGF R, HGF receptor, HGF/SF receptor, HGFR, MET, Met (c-Met), met proto-oncogene (hepatocyte growth factor receptor), met proto-oncogene tyrosine kinase, oncogene MET, Proto-oncogene c-Met, RCCP2, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.