product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human VEGFR2/KDR/Flk-1 Antibody
catalog :
MAB3573-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
89109
reactivity :
human
application :
western blot, ELISA, neutralization
more info or order :
citations: 6
Reference
Landry J, Fei Y, Zhu X, Ke Y, Yu G, Lee P. Discovering small molecule ligands of vascular endothelial growth factor that block VEGF-KDR binding using label-free microarray-based assays. Assay Drug Dev Technol. 2013;11:326-32 pubmed publisher
Niland S, Ditkowski B, Parrandier D, Roth L, Augustin H, Eble J. Rhodocetin-αβ-induced neuropilin-1-cMet association triggers restructuring of matrix contacts in endothelial cells. Arterioscler Thromb Vasc Biol. 2013;33:544-54 pubmed publisher
Meissner M, Reichenbach G, Stein M, Hrgovic I, Kaufmann R, Gille J. Down-regulation of vascular endothelial growth factor receptor 2 is a major molecular determinant of proteasome inhibitor-mediated antiangiogenic action in endothelial cells. Cancer Res. 2009;69:1976-84 pubmed publisher
Wen J, Fu A, Chen L, Xie X, Yang G, Chen X, et al. Liposomal honokiol inhibits VEGF-D-induced lymphangiogenesis and metastasis in xenograft tumor model. Int J Cancer. 2009;124:2709-18 pubmed publisher
Kobune M, Kawano Y, Takahashi S, Takada K, Murase K, Iyama S, et al. Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin(-)CD34(-) cells. Exp Hematol. 2008;36:1121-31 pubmed publisher
Oliner J, Min H, Leal J, Yu D, Rao S, You E, et al. Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2. Cancer Cell. 2004;6:507-16 pubmed
product information
brand :
R&D Systems
master code :
MAB3573
SKU :
MAB3573-100
product name :
Human VEGFR2/KDR/Flk-1 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Human VEGFR2/KDR/Flk-1 Antibody from R&D Systems is a mouse monoclonal antibody to VEGFR2/KDR/Flk-1. This antibody reacts with human. The Human VEGFR2/KDR/Flk-1 Antibody has been validated for the following applications: ELISA Development,Western Blot,Neutralization,ELISA Capture (Matched Antibody Pair).
target :
VEGFR2/KDR/Flk-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
89109
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGFR2/KDR/Flk-1, Ala20-Glu764, Accession # P35968
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human VEGFR2/KDR/Flk-1 in ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) VEGFR1, rhVEGFR3, or recombinant mouse VEGFR2 is observed.
gene symbol :
KDR
accessionNumbers :
P35968
applications :
ELISA Capture (Matched Antibody Pair),ELISA Development,Western Blot,Neutralization
USD :
469 USD
alt names :
CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, Flk1, Flk-1, FLK1tyrosine kinase growth factor receptor, KDR, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), KRD1, Ly73, Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGF R2, VEGFR, VEGFR2, VEGFR-2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.