Human VEGFR2/KDR/Flk-1 Antibody | R&D Systems MAB3572-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human VEGFR2/KDR/Flk-1 Antibody

catalog :

MAB3572-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

89106

reactivity :

human, mouse, rhesus macaque

application :

neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 36

Reference
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Ko S, Lee W, Kenny H, Dang L, Ellis L, Jonasch E, et al. Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake. Commun Biol. 2019;2:386 pubmed publisher
Toledo Pons N, Noell G, Jahn A, Iglesias A, Durán M, Iglesias J, et al. Bone marrow characterization in COPD: a multi-level network analysis. Respir Res. 2018;19:118 pubmed publisher
Chen L, Okeke E, Ayalew D, Wang D, Shahid L, Dokun A. Modulation of miR29a improves impaired post-ischemic angiogenesis in hyperglycemia. Exp Biol Med (Maywood). 2017;242:1432-1443 pubmed publisher
Otto S, Nitsche K, Jung C, Kryvanos A, Zhylka A, Heitkamp K, et al. Endothelial progenitor cells and plaque burden in stented coronary artery segments: an optical coherence tomography study six months after elective PCI. BMC Cardiovasc Disord. 2017;17:103 pubmed publisher
Indrakusuma I, Romacho T, Eckel J. Protease-Activated Receptor 2 Promotes Pro-Atherogenic Effects through Transactivation of the VEGF Receptor 2 in Human Vascular Smooth Muscle Cells. Front Pharmacol. 2016;7:497 pubmed publisher
Odent Grigorescu G, Rosca A, Preda M, Tutuianu R, Simionescu M, Burlacu A. Synergic effects of VEGF-A and SDF-1 on the angiogenic properties of endothelial progenitor cells. J Tissue Eng Regen Med. 2017;11:3241-3252 pubmed publisher
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Arnott C, Punnia Moorthy G, Tan J, Sadeghipour S, Bursill C, Patel S. The Vascular Endothelial Growth Factor Inhibitors Ranibizumab and Aflibercept Markedly Increase Expression of Atherosclerosis-Associated Inflammatory Mediators on Vascular Endothelial Cells. PLoS ONE. 2016;11:e0150688 pubmed publisher
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product information

master code :

MAB3572

SKU :

MAB3572-100

product name :

Human VEGFR2/KDR/Flk-1 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human VEGFR2/KDR/Flk-1 Antibody from R&D Systems is a mouse monoclonal antibody to VEGFR2/KDR/Flk-1. This antibody reacts with human,mouse,primate - macaca mulatta (rhesus macaque). The Human VEGFR2/KDR/Flk-1 Antibody has been validated for the following applications: Neutralization,Flow Cytometry,CyTOF-ready.

target :

VEGFR2/KDR/Flk-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

89106

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGFR2/KDR/Flk-1, Ala20-Glu764, Accession # P35968

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Primate - Macaca mulatta (Rhesus Macaque)

specificity :

Detects human VEGFR2/KDR/Flk-1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) VEGFR1, rhVEGFR3 or recombinant mouse VEGFR2 is observed.

gene symbol :

KDR

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of VEGFR2/KDR/Flk-1 antibody in HUVEC Human Cells antibody by Flow Cytometry.

accessionNumbers :

P35968

applications :

Flow Cytometry,Neutralization,CyTOF-ready

USD :

469 USD

alt names :

CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, Flk1, Flk-1, FLK1tyrosine kinase growth factor receptor, KDR, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), KRD1, Ly73, Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGF R2, VEGFR, VEGFR2, VEGFR-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage