Human VEGFR2/KDR/Flk-1 Antibody | R&D Systems MAB3571-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human VEGFR2/KDR/Flk-1 Antibody

catalog :

MAB3571-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

89115

reactivity :

human, mouse, rhesus macaque

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 23

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; fig 3d	Yang C, Eleftheriadou M, Kelaini S, Morrison T, González M, Caines R, et al. Targeting QKI-7 in vivo restores endothelial cell function in diabetes. Nat Commun. 2020;11:3812 pubmed publisher
	Bansal A, Singh A, Nag T, Sharma D, Garg B, Bhatla N, et al. Augmenting the Angiogenic Profile and Functionality of Cord Blood Endothelial Colony-Forming Cells by Indirect Priming with Bone-Marrow-Derived Mesenchymal Stromal Cells. Biomedicines. 2023;11: pubmed publisher
	Sen A, Singh A, Roy A, Mohanty S, Naik N, Kalaivani M, et al. Role of endothelial colony forming cells (ECFCs) Tetrahydrobiopterin (BH4) in determining ECFCs functionality in coronary artery disease (CAD) patients. Sci Rep. 2022;12:3076 pubmed publisher
	Dayton J, Yuan Y, Pacumio L, Dorflinger B, Yoo S, Olson M, et al. Expression of IL-20 Receptor Subunit β Is Linked to EAE Neuropathology and CNS Neuroinflammation. Front Cell Neurosci. 2021;15:683687 pubmed publisher
	Estrella Mendoza M, Jiménez Gómez F, López Ornelas A, Perez Gutierrez R, Flores Estrada J. Cucurbita argyrosperma Seed Extracts Attenuate Angiogenesis in a Corneal Chemical Burn Model. Nutrients. 2019;11: pubmed publisher
	Seyed Jafari S, Wiedmer C, Cazzaniga S, Frangez Z, Shafighi M, Beltraminelli H, et al. Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE. 2018;13:e0207019 pubmed publisher
	Vil xe0 Gonz xe1 lez M, Kelaini S, Magee C, Caines R, Campbell D, Eleftheriadou M, et al. Enhanced Function of Induced Pluripotent Stem Cell-Derived Endothelial Cells Through ESM1 Signaling. Stem Cells. 2019;37:226-239 pubmed publisher
	Li H, Teng Y, Xu X, Liu J. Enhanced rapamycin delivery to hemangiomas by lipid polymer nanoparticles coupled with anti-VEGFR antibody. Int J Mol Med. 2018;41:3586-3596 pubmed publisher
	Li X, Ren X, Liang J, Ma W, Wang Z, Yang Z. Delivery of sodium morrhuate to hemangioma endothelial cells using immunoliposomes conjugated with anti-VEGFR2/KDR antibody. Int J Nanomedicine. 2017;12:6963-6972 pubmed publisher
	Zhao W, Xu S, Liang J, Peng L, Liu H, Wang Z, et al. Endothelial progenitor cells from human fetal aorta cure diabetic foot in a rat model. Metabolism. 2016;65:1755-1767 pubmed publisher
	D Alessio A, Proietti G, Lama G, Biamonte F, Lauriola L, Moscato U, et al. Analysis of angiogenesis related factors in glioblastoma, peritumoral tissue and their derived cancer stem cells. Oncotarget. 2016;7:78541-78556 pubmed publisher
	Selvaraj D, Gangadharan V, Michalski C, Kurejova M, StÃ¶sser S, Srivastava K, et al. A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain. Cancer Cell. 2015;27:780-96 pubmed publisher
	Kim H, Kim K, Kim B, Cho M, Lee S. The effect of vascular endothelial growth factor on osteoclastogenesis in rheumatoid arthritis. PLoS ONE. 2015;10:e0124909 pubmed publisher
	dela Paz N, Melchior B, Frangos J. Early VEGFR2 activation in response to flow is VEGF-dependent and mediated by MMP activity. Biochem Biophys Res Commun. 2013;434:641-6 pubmed publisher
	Niwa A, Heike T, Umeda K, Oshima K, Kato I, Sakai H, et al. A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors. PLoS ONE. 2011;6:e22261 pubmed publisher
	Muscari C, Gamberini C, Basile I, Bonafe F, Valgimigli S, Capitani O, et al. Comparison between Culture Conditions Improving Growth and Differentiation of Blood and Bone Marrow Cells Committed to the Endothelial Cell Lineage. Biol Proced Online. 2010;12:9023 pubmed publisher
	Malla R, Gopinath S, Gondi C, Alapati K, Dinh D, Gujrati M, et al. Cathepsin B and uPAR knockdown inhibits tumor-induced angiogenesis by modulating VEGF expression in glioma. Cancer Gene Ther. 2011;18:419-34 pubmed publisher
	Ricci Vitiani L, Pallini R, Biffoni M, Todaro M, Invernici G, Cenci T, et al. Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature. 2010;468:824-8 pubmed publisher
	Zhu C, Ying D, Mi J, Li L, Zeng W, Hou C, et al. Development of anti-atherosclerotic tissue-engineered blood vessel by A20-regulated endothelial progenitor cells seeding decellularized vascular matrix. Biomaterials. 2008;29:2628-36 pubmed publisher
	Lin H, Shabbir A, Molnar M, Yang J, Marion S, Canty J, et al. Adenoviral expression of vascular endothelial growth factor splice variants differentially regulate bone marrow-derived mesenchymal stem cells. J Cell Physiol. 2008;216:458-68 pubmed publisher
	Srivastava A, Nedelcu E, Esmaeli Azad B, Mishra R, Carrier E. Thrombopoietin enhances generation of CD34+ cells from human embryonic stem cells. Stem Cells. 2007;25:1456-61 pubmed
	Yang X, Man X, Cai S, Yao Y, Bu Z, Zheng M. Expression of VEGFR-2 on HaCaT cells is regulated by VEGF and plays an active role in mediating VEGF induced effects. Biochem Biophys Res Commun. 2006;349:31-8 pubmed
	Bussolati B, Bruno S, Grange C, Buttiglieri S, Deregibus M, Cantino D, et al. Isolation of renal progenitor cells from adult human kidney. Am J Pathol. 2005;166:545-55 pubmed

product information

master code :

MAB3571

SKU :

MAB3571-100

product name :

Human VEGFR2/KDR/Flk-1 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human VEGFR2/KDR/Flk-1 Antibody from R&D Systems is a mouse monoclonal antibody to VEGFR2/KDR/Flk-1. This antibody reacts with human,mouse,porcine,primate - macaca mulatta (rhesus macaque),rat. The Human VEGFR2/KDR/Flk-1 Antibody has been validated for the following applications: Immunohistochemistry,Drug Delivery,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry.

target :

VEGFR2/KDR/Flk-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

89115

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGFR2, Ala20-Glu764, Accession # P35968

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human,Mouse,Porcine,Primate - Macaca mulatta (Rhesus Macaque)

specificity :

Detects human VEGFR2 in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant human (rh) VEGFR1, rhVEGFR3, or recombinant mouse VEGFR2.

gene symbol :

KDR

top caption :

VEGFR2/KDR/Flk-1 antibody in Human Placenta by Immunohistochemistry (IHC-P).

accessionNumbers :

P35968

applications :

Drug Delivery,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry

USD :

459 USD

alt names :

CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, Flk1, Flk-1, FLK1tyrosine kinase growth factor receptor, KDR, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), KRD1, Ly73, Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGF R2, VEGFR, VEGFR2, VEGFR-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage