product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Phospho-EGFR (Y1068) Antibody
catalog :
MAB3570
quantity :
100 ug (also 25 ug)
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
338324
reactivity :
human
application :
western blot
more info or order :
citations: 9
Reference
Schek N, Lee J, Burslem G, Witze E. Chemical probe mediated visualization of protein S-palmitoylation in patient tissue samples. Front Physiol. 2023;14:1063247 pubmed publisher
Fan F, Zhou M, Ye X, Mo Z, Ma Y, Luo L, et al. BEBT-109, a pan-mutant-selective EGFR inhibitor with potent antitumor activity in EGFR-mutant non-small cell lung cancer. Transl Oncol. 2021;14:100961 pubmed publisher
Ju L, Dong Z, Yang J, Li M. Mechanism of intrinsic resistance of lung squamous cell carcinoma to epithelial growth factor receptor-tyrosine kinase inhibitors revealed by high-throughput RNA interference screening. Oncol Lett. 2020;20:363 pubmed publisher
Le P, Lim S, Baculis B, Chung H, Kilian K, Smith A. Counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions. Nat Commun. 2019;10:909 pubmed publisher
Basova L, Najera J, Bortell N, Wang D, Moya R, Lindsey A, et al. Dopamine and its receptors play a role in the modulation of CCR5 expression in innate immune cells following exposure to Methamphetamine: Implications to HIV infection. PLoS ONE. 2018;13:e0199861 pubmed publisher
Lindberg O, McKinney A, Engler J, Koshkakaryan G, Gong H, Robinson A, et al. GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity. Oncotarget. 2016;7:79101-79116 pubmed publisher
Sakanyan V, Hulin P, Alves de Sousa R, Silva V, Hambardzumyan A, Nedellec S, et al. Activation of EGFR by small compounds through coupling the generation of hydrogen peroxide to stable dimerization of Cu/Zn SOD1. Sci Rep. 2016;6:21088 pubmed publisher
Cross D, Ashton S, Ghiorghiu S, Eberlein C, Nebhan C, Spitzler P, et al. AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discov. 2014;4:1046-61 pubmed publisher
Lee K, Yun S, Yun C, Ahn B, Jo E. S100A2 promoter-driven conditionally replicative adenovirus targets non-small-cell lung carcinoma. Gene Ther. 2012;19:967-77 pubmed publisher
product information
master code :
MAB3570
SKU :
MAB3570
product name :
Human Phospho-EGFR (Y1068) Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Phospho-EGFR (Y1068) Antibody from R&D Systems is a mouse monoclonal antibody to EGFR. This antibody reacts with human. The Human Phospho-EGFR (Y1068) Antibody has been validated for the following applications: Immunocytochemistry,Western Blot,Intracellular Staining by Flow Cytometry,CyTOF-ready.
target :
EGFR
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
338324
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Phosphopeptide containing human EGFR Y1068 site
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human EGFR phosphorylated at Y1068.
gene symbol :
EGFR
top caption :
Detection of Human Phospho-EGFR (Y1068) antibody by Western Blot.
applications :
Western Blot,Intracellular Staining by Flow Cytometry,CyTOF-ready
USD :
439 USD
alt names :
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, EGF R, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ErbB, ErbB1, ERBB1PIG61, HER1, HER-1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.