This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human BMP-2/BMP-4 Antibody
catalog :
MAB3552
quantity :
100 ug (also 25 ug, 500 ug)
price :
359 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
100230
reactivity :
human
application :
western blot, neutralization
citations: 6
Reference
Martínez V, Sacedón R, Hidalgo L, Valencia J, Fernández Sevilla L, Hernández López C, et al. The BMP Pathway Participates in Human Naive CD4+ T Cell Activation and Homeostasis. PLoS ONE. 2015;10:e0131453 pubmed publisher
Boswell B, Overbeek P, Musil L. Essential role of BMPs in FGF-induced secondary lens fiber differentiation. Dev Biol. 2008;324:202-12 pubmed publisher
Southwood M, Jeffery T, Yang X, Upton P, Hall S, Atkinson C, et al. Regulation of bone morphogenetic protein signalling in human pulmonary vascular development. J Pathol. 2008;214:85-95 pubmed
Lin L, Valore E, Nemeth E, Goodnough J, Gabayan V, Ganz T. Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4. Blood. 2007;110:2182-9 pubmed
Rydziel S, Stadmeyer L, Zanotti S, Durant D, Smerdel Ramoya A, Canalis E. Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia. J Biol Chem. 2007;282:19762-72 pubmed
Zhao M, Zhao Z, Koh J, Jin T, Franceschi R. Combinatorial gene therapy for bone regeneration: cooperative interactions between adenovirus vectors expressing bone morphogenetic proteins 2, 4, and 7. J Cell Biochem. 2005;95:1-16 pubmed
product information
brand :
R&D Systems
master code :
MAB3552
SKU :
MAB3552-100
product name :
Human BMP-2/BMP-4 Antibody
description :
The Human BMP-2/BMP-4 Antibody from R&D Systems is a mouse monoclonal antibody to BMP-2/BMP-4. This antibody reacts with human. The Human BMP-2/BMP-4 Antibody has been validated for the following applications: Western Blot, Neutralization.
target :
BMP-2/BMP-4
category :
Primary Antibodies
unit size :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
100230
conjugate :
Unconjugated
host :
Mouse
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant human BMP-2, Gln283-Arg396, Accession # P12643
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human BMP-2 and human BMP-4 in direct ELISAs and Western blots. In direct ELISAs, 100% cross-reactivity with recombinant zebra fish (rzf) BMP-2 and rhBMP-4, 20%-40% cross-reactivity with rhBMP-3, -3b, -6, and no cross-reactivity with rhBMP-5, -7, -10, or -15 is observed.
gene symbol :
BMP2
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB3552
accessionNumbers :
P12643
applications :
Western Blot, Neutralization
2020 USD :
339
2021 USD :
359 USD
alt names :
BDA2, BMP2, BMP-2, BMP2A, BMP-2A, BMP2ABone morphogenetic protein 2A, BMP2B, BMP2B1, BMP4, bone morphogenetic protein 2, MCOPS6, OFC11, SSFSC
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.