Human BMP-2 Antibody | R&D Systems MAB3551 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human BMP-2 Antibody

catalog :

MAB3551

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

100221

reactivity :

human

application :

western blot, ELISA

citations: 10

Reference
Cheng Z, Alba Perez A, González García C, Donnelly H, Llopis Hernández V, Jayawarna V, et al. Nanoscale Coatings for Ultralow Dose BMP-2-Driven Regeneration of Critical-Sized Bone Defects. Adv Sci (Weinh). 2019;6:1800361 pubmed publisher
Hurst L, Dunmore B, Long L, Crosby A, Al Lamki R, Deighton J, et al. TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling. Nat Commun. 2017;8:14079 pubmed publisher
Chang C, Yeh S, Lee B, Chen C, Su C, Lin Y, et al. Osteogenic Surface Modification Based on Functionalized Poly-P-Xylylene Coating. PLoS ONE. 2015;10:e0137017 pubmed publisher
Du Y, Xiao Q, Yip H. Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade. Invest Ophthalmol Vis Sci. 2010;51:3764-73 pubmed publisher
Chen Y, Chen P, Jeng L, Huang C, Yang L, Chung H, et al. Periodontal regeneration using ex vivo autologous stem cells engineered to express the BMP-2 gene: an alternative to alveolaplasty. Gene Ther. 2008;15:1469-77 pubmed publisher
Kane R, Godson C, O Brien C. Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis. Mol Vis. 2008;14:1138-48 pubmed
Sengle G, Charbonneau N, Ono R, Sasaki T, Alvarez J, Keene D, et al. Targeting of bone morphogenetic protein growth factor complexes to fibrillin. J Biol Chem. 2008;283:13874-88 pubmed publisher
Kuns Hashimoto R, Kuninger D, Nili M, Rotwein P. Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin. Am J Physiol Cell Physiol. 2008;294:C994-C1003 pubmed publisher
Dai J, Keller J, Zhang J, Lu Y, Yao Z, Keller E. Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. Cancer Res. 2005;65:8274-85 pubmed
Kayed H, Kleeff J, Keleg S, Guo J, Ketterer K, Berberat P, et al. Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer. Int J Cancer. 2004;110:668-76 pubmed

product information

brand :

R&D Systems

master code :

MAB3551

SKU :

MAB3551-100

product name :

Human BMP-2 Antibody

description :

The Human BMP-2 Antibody from R&D Systems is a mouse monoclonal antibody to BMP-2. This antibody reacts with human. The Human BMP-2 Antibody has been validated for the following applications: Western Blot, ELISA Capture (Matched Antibody Pair).

target :

BMP-2

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

100221

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human BMP-2, Gln283-Arg396, Accession # P12643

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human BMP-2 in ELISAs and Western blots. In Western blots, this antibody shows less than 1% cross-reactivity with recombinant human (rh) BMP-3, rhBMP-4, rhBMP-5, rhBMP-6, or rhBMP-7.

gene symbol :

BMP2

catalog number base :

MAB3551

accessionNumbers :

P12643

applications :

Western Blot, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

359 USD

alt names :

BDA2, BMP2, BMP-2, BMP-2A, BMP2ABone morphogenetic protein 2A, bone morphogenetic protein 2, SSFSC

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.