Human BMP-7 Antibody | R&D Systems MAB3542-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human BMP-7 Antibody

catalog :

MAB3542-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

164313

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 8

Reference
Cate R, di Clemente N, Racine C, Groome N, Pepinsky R, Whitty A. The anti-Müllerian hormone prodomain is displaced from the hormone/prodomain complex upon bivalent binding to the hormone receptor. J Biol Chem. 2022;298:101429 pubmed publisher
Kim S, Jeong C, Song S, Um J, Kim H, Yun J, et al. Micellized Protein Transduction Domain-Bone Morphogenetic Protein-7 Efficiently Blocks Renal Fibrosis Via Inhibition of Transforming Growth Factor-Beta-Mediated Epithelial-Mesenchymal Transition. Front Pharmacol. 2020;11:591275 pubmed publisher
Bouty A, Walton K, Listyasari N, Robevska G, van den Bergen J, Santosa A, et al. Functional Characterization of Two New Variants in the Bone Morphogenetic Protein 7 Prodomain in Two Pairs of Monozygotic Twins With Hypospadias. J Endocr Soc. 2019;3:814-824 pubmed publisher
Wohl A, Troilo H, Collins R, Baldock C, Sengle G. Extracellular Regulation of Bone Morphogenetic Protein Activity by the Microfibril Component Fibrillin-1. J Biol Chem. 2016;291:12732-46 pubmed publisher
Camara Clayette V, Koscielny S, Roux S, Lamy T, Bosq J, Bernard M, et al. BMP7 expression correlates with secondary drug resistance in mantle cell lymphoma. PLoS ONE. 2013;8:e73993 pubmed publisher
Khan I, Kumar N, Pant I, Narra S, Kondaiah P. Activation of TGF-? pathway by areca nut constituents: a possible cause of oral submucous fibrosis. PLoS ONE. 2012;7:e51806 pubmed publisher
Csomor P, Liktor B, Liktor B, Szekanecz Z, Sziklai I, Karosi T. Expression of bone morphogenetic protein 2, 4, 5, and 7 correlates with histological activity of otosclerotic foci. Acta Otolaryngol. 2012;132:624-31 pubmed publisher
Dai J, Keller J, Zhang J, Lu Y, Yao Z, Keller E. Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. Cancer Res. 2005;65:8274-85 pubmed

product information

master code :

MAB3542

SKU :

MAB3542-100

product name :

Human BMP-7 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human BMP-7 Antibody from R&D Systems is a mouse monoclonal antibody to BMP-7. This antibody reacts with human. The Human BMP-7 Antibody has been validated for the following applications: Neutralization,Western Blot,ELISA Detection,Immunohistochemistry,ELISA Capture (Matched Antibody Pair).

target :

BMP-7

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

164313

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human BMP-7, Arg292-His431, Accession # P18075

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human BMP-7 in ELISAs. In ELISAs, this antibody shows approximately 25-50% cross-reactivity with recombinant human (rh) BMP-6 and no cross-reactivity with rhBMP-2, -3, -4, -5, or -8.

gene symbol :

BMP7

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Alkaline Phosphatase Production Induced by BMP-7 and Neutralization by Human BMP-7 Antibody.

accessionNumbers :

P18075

applications :

Western Blot,ELISA Detection,Immunohistochemistry,Neutralization,ELISA Capture (Matched Antibody Pair)

USD :

459 USD

alt names :

BMP7, BMP-7, bone morphogenetic protein 7, Eptotermin alfa, OP-1, OP-1OP1, Osteogenic protein 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage