Human BMP-7 Antibody | R&D Systems MAB3541 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human BMP-7 Antibody

catalog :

MAB3541

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

164311

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; loading ...; fig 1a, 1d immunocytochemistry; human; fig 1e	Veschi V, Mangiapane L, Nicotra A, Di Franco S, Scavo E, Apuzzo T, et al. Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant. Oncogene. 2020;39:987-1003 pubmed publisher
	Blanchette Farra N, Kita D, Konstorum A, Tesfay L, Lemler D, Hegde P, et al. Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer. Oncogene. 2018;37:4013-4032 pubmed publisher
	Du Y, Xiao Q, Yip H. Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade. Invest Ophthalmol Vis Sci. 2010;51:3764-73 pubmed publisher
	Sengle G, Ono R, Lyons K, Bachinger H, Sakai L. A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7. J Mol Biol. 2008;381:1025-39 pubmed publisher
	Hsu M, Rovinsky S, Lai C, Qasem S, Liu X, How J, et al. Aggressive melanoma cells escape from BMP7-mediated autocrine growth inhibition through coordinated Noggin upregulation. Lab Invest. 2008;88:842-55 pubmed publisher
	Sengle G, Charbonneau N, Ono R, Sasaki T, Alvarez J, Keene D, et al. Targeting of bone morphogenetic protein growth factor complexes to fibrillin. J Biol Chem. 2008;283:13874-88 pubmed publisher
	Zhao M, Zhao Z, Koh J, Jin T, Franceschi R. Combinatorial gene therapy for bone regeneration: cooperative interactions between adenovirus vectors expressing bone morphogenetic proteins 2, 4, and 7. J Cell Biochem. 2005;95:1-16 pubmed

product information

brand :

R&D Systems

master code :

MAB3541

SKU :

MAB3541-100

product name :

Human BMP-7 Antibody

description :

The Human BMP-7 Antibody from R&D Systems is a mouse monoclonal antibody to BMP-7. This antibody reacts with human. The Human BMP-7 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Neutralization.

target :

BMP-7

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Supplied as a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

164311

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human BMP-7, Ser293-His431, Accession # P18075

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human BMP-7 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human (rh) BMP-6 is observed and no cross-reactivity with rhBMP-2, -3, -4, -5, or -8 is observed.

gene symbol :

BMP7

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB3541

accessionNumbers :

P18075

applications :

Western Blot, Immunohistochemistry, Neutralization

2020 USD :

339

2021 USD :

359 USD

alt names :

BMP7, BMP-7, bone morphogenetic protein 7, Eptotermin alfa, OP-1, OP-1OP1, Osteogenic protein 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C, as supplied. 1 month, 2 to 8 °C under sterile conditions after opening. 6 months, -20 to -70 °C under sterile conditions after opening.