Human BMP-7 Antibody | R&D Systems MAB3541-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human BMP-7 Antibody

catalog :

MAB3541-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

164311

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 11

Reference
Oude Egberink R, Zegelaar H, El Boujnouni N, Versteeg E, Daamen W, Brock R. Biomaterial-Mediated Protein Expression Induced by Peptide-mRNA Nanoparticles Embedded in Lyophilized Collagen Scaffolds. Pharmaceutics. 2022;14: pubmed publisher
Kim M, Kim C, Kim Y, Jang J, Lee G. Selective endocytosis of recombinant human BMPs through cell surface heparan sulfate proteoglycans in CHO cells: BMP-2 and BMP-7. Sci Rep. 2021;11:3378 pubmed publisher
Veschi V, Mangiapane L, Nicotra A, Di Franco S, Scavo E, Apuzzo T, et al. Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant. Oncogene. 2020;39:987-1003 pubmed publisher
Blanchette Farra N, Kita D, Konstorum A, Tesfay L, Lemler D, Hegde P, et al. Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer. Oncogene. 2018;37:4013-4032 pubmed publisher
Tandon A, Sharma A, Rodier J, Klibanov A, Rieger F, Mohan R. BMP7 gene transfer via gold nanoparticles into stroma inhibits corneal fibrosis in vivo. PLoS ONE. 2013;8:e66434 pubmed publisher
Liu Y, Chen J, Yang Y, Zhang L, Jiang W. ?olecular impact of bone morphogenetic protein 7, on lung cancer cells and its clinical significance. Int J Mol Med. 2012;29:1016-24 pubmed publisher
Du Y, Xiao Q, Yip H. Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade. Invest Ophthalmol Vis Sci. 2010;51:3764-73 pubmed publisher
Sengle G, Ono R, Lyons K, Bachinger H, Sakai L. A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7. J Mol Biol. 2008;381:1025-39 pubmed publisher
Hsu M, Rovinsky S, Lai C, Qasem S, Liu X, How J, et al. Aggressive melanoma cells escape from BMP7-mediated autocrine growth inhibition through coordinated Noggin upregulation. Lab Invest. 2008;88:842-55 pubmed publisher
Sengle G, Charbonneau N, Ono R, Sasaki T, Alvarez J, Keene D, et al. Targeting of bone morphogenetic protein growth factor complexes to fibrillin. J Biol Chem. 2008;283:13874-88 pubmed publisher
Zhao M, Zhao Z, Koh J, Jin T, Franceschi R. Combinatorial gene therapy for bone regeneration: cooperative interactions between adenovirus vectors expressing bone morphogenetic proteins 2, 4, and 7. J Cell Biochem. 2005;95:1-16 pubmed

product information

master code :

MAB3541

SKU :

MAB3541-100

product name :

Human BMP-7 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human BMP-7 Antibody from R&D Systems is a mouse monoclonal antibody to BMP-7. This antibody reacts with hamster,human,mouse. The Human BMP-7 Antibody has been validated for the following applications: Western Blot,ELISA Development,ELISA,Immunoprecipitation,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry.

target :

BMP-7

category :

Primary Antibodies

buffer :

Supplied as a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

164311

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human BMP-7, Ser293-His431, Accession # P18075

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Hamster,Human,Mouse

specificity :

Detects human BMP-7 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human (rh) BMP-6 is observed and no cross-reactivity with rhBMP-2, -3, -4, -5, or -8 is observed.

gene symbol :

BMP7

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Alkaline Phosphatase Production Induced by BMP-7 and Neutralization by Human BMP-7 Antibody.

accessionNumbers :

P18075

applications :

Western Blot,ELISA Development,ELISA,Immunoprecipitation,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry

USD :

469 USD

alt names :

BMP7, BMP-7, bone morphogenetic protein 7, Eptotermin alfa, OP-1, OP-1OP1, Osteogenic protein 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C, as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening. 6 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage