VEGFR3/Flt-4 Antibody | R&D Systems MAB3491-100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

VEGFR3/Flt-4 Antibody

catalog :

MAB3491-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

54703

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 6

Reference
Chakraborty A, Scogin C, Rizwan K, Morley T, Rutkowski J. Characterizing Lymphangiogenesis and Concurrent Inflammation in Adipose Tissue in Response to VEGF-D. Front Physiol. 2020;11:363 pubmed publisher
Seyed Jafari S, Wiedmer C, Cazzaniga S, Frangez Z, Shafighi M, Beltraminelli H, et al. Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE. 2018;13:e0207019 pubmed publisher
Goertz L, Schneider S, Desch A, Mayer F, Koett J, Nowak K, et al. Heparins that block VEGF-A-mediated von Willebrand factor fiber generation are potent inhibitors of hematogenous but not lymphatic metastasis. Oncotarget. 2016;7:68527-68545 pubmed publisher
Su J, Chen P, Chien M, Chen P, Chen Y, Lai C, et al. Further evidence for expression and function of the VEGF-C/VEGFR-3 axis in cancer cells. Cancer Cell. 2008;13:557-60 pubmed publisher
Ball S, Shuttleworth C, Kielty C. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors. J Cell Biol. 2007;177:489-500 pubmed
Su J, Yang P, Shih J, Yang C, Wei L, Hsieh C, et al. The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells. Cancer Cell. 2006;9:209-23 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB3491

SKU :

MAB3491-100

product name :

VEGFR3/Flt-4 Antibody

Description :

The Human VEGFR3/Flt-4 Antibody from R&D Systems is a mouse monoclonal antibody to VEGFR3/Flt-4. This antibody reacts with human. The Human VEGFR3/Flt-4 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry.

target :

VEGFR3/Flt-4

category :

Primary Antibodies

unit size :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

54703

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human VEGFR3/Flt-4, Tyr25-Ile776, Accession # P35916

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human VEGFR3/Flt-4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25-30% cross-reactivity with recombinant mouse VEGFR3 is observed and no cross-reactivity with recombinant human (rh) VEGFR1 or rhVEGFR2 is observed.

gene symbol :

FLT4

accessionNumbers :

P35916

applications :

Western Blot, Immunohistochemistry, Immunocytochemistry

USD :

459 USD

alt names :

EC 2.7.10, EC 2.7.10.1, Flt-4, FLT4, fms-related tyrosine kinase 4, LMPH1A, PCLFLT41, soluble VEGFR3 variant 1, soluble VEGFR3 variant 2, soluble VEGFR3 variant 3, Tyrosine-protein kinase receptor FLT4, vascular endothelial growth factor receptor 3, VEGF R3, VEGFR-3, VEGFR3Fms-like tyrosine kinase 4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.