Human ErbB3/Her3 Antibody | R&D Systems MAB3481 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human ErbB3/Her3 Antibody

catalog :

MAB3481

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

66223

reactivity :

human

application :

western blot, ELISA, neutralization, flow cytometry

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 3	Wang J, Wuethrich A, Sina A, Lane R, Lin L, Wang Y, et al. Tracking extracellular vesicle phenotypic changes enables treatment monitoring in melanoma. Sci Adv. 2020;6:eaax3223 pubmed publisher
flow cytometry; human; loading ...; fig s2a	Kabanova A, Marcandalli J, Zhou T, Bianchi S, Baxa U, Tsybovsky Y, et al. Platelet-derived growth factor-Î± receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer. Nat Microbiol. 2016;1:16082 pubmed publisher
flow cytometry; human; loading ...; tbl 2 western blot; human; loading ...; fig 4	Ioannou N, Seddon A, Dalgleish A, Mackintosh D, Solca F, Modjtahedi H. Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition. Int J Oncol. 2016;48:908-18 pubmed publisher
	Wang J, Anderson W, Li J, Lin L, Wang Y, Trau M. A high-resolution study of in situ surface-enhanced Raman scattering nanotag behavior in biological systems. J Colloid Interface Sci. 2019;537:536-546 pubmed publisher
	Memon A, Gilliver S, Borre M, Sundquist J, Sundquist K, Nexo E, et al. Soluble HER3 predicts survival in bladder cancer patients. Oncol Lett. 2018;15:1783-1788 pubmed publisher
	Le Clorennec C, BAZIN H, Dubreuil O, Larbouret C, Ogier C, Lazrek Y, et al. Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3. Mol Cancer Ther. 2017;16:1312-1323 pubmed publisher
	Puvanenthiran S, Essapen S, Seddon A, Modjtahedi H. Impact of the putative cancer stem cell markers and growth factor receptor expression on the sensitivity of ovarian cancer cells to treatment with various forms of small molecule tyrosine kinase inhibitors and cytotoxic drugs. Int J Oncol. 2016;49:1825-1838 pubmed publisher
	Fock V, Plessl K, Draxler P, Otti G, Fiala C, KnÃ¶fler M, et al. Neuregulin-1-mediated ErbB2-ErbB3 signalling protects human trophoblasts against apoptosis to preserve differentiation. J Cell Sci. 2015;128:4306-16 pubmed publisher
	Liu Z, Leng E, Gunasekaran K, Pentony M, Shen M, Howard M, et al. A novel antibody engineering strategy for making monovalent bispecific heterodimeric IgG antibodies by electrostatic steering mechanism. J Biol Chem. 2015;290:7535-62 pubmed publisher
	Khelwatty S, Essapen S, Seddon A, Modjtahedi H. Growth response of human colorectal tumour cell lines to treatment with afatinib (BIBW2992), an irreversible erbB family blocker, and its association with expression of HER family members. Int J Oncol. 2011;39:483-91 pubmed publisher
	Khan I, Zhao J, Ghosh P, Ziman M, Sweeney C, Kung H, et al. Microbead arrays for the analysis of ErbB receptor tyrosine kinase activation and dimerization in breast cancer cells. Assay Drug Dev Technol. 2010;8:27-36 pubmed publisher
	Lin S, Lee Y, Choueiri M, Wen S, Mathew P, Ye X, et al. Soluble ErbB3 levels in bone marrow and plasma of men with prostate cancer. Clin Cancer Res. 2008;14:3729-36 pubmed publisher
	Lin S, Cheng C, Lee Y, Ye X, Tsai W, Kim J, et al. A 45-kDa ErbB3 secreted by prostate cancer cells promotes bone formation. Oncogene. 2008;27:5195-203 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB3481

SKU :

MAB3481-100

product name :

Human ErbB3/Her3 Antibody

description :

The Human ErbB3/Her3 Antibody from R&D Systems is a mouse monoclonal antibody to ErbB3/Her3. This antibody reacts with human. The Human ErbB3/Her3 Antibody has been validated for the following applications: Flow Cytometry, Neutralization, CyTOF-ready, ELISA Capture (Matched Antibody Pair).

target :

ErbB3/Her3

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

66223

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human ErbB3/Her3, Ser20-Thr643, Accession # P21860

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human ErbB3/Her3 in ELISAs. Does not cross-react with recombinant EGF R.

gene symbol :

ERBB3

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB3481

accessionNumbers :

P21860

applications :

Flow Cytometry, Neutralization, CyTOF-ready, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

359 USD

alt names :

c-erbB3, EC 2.7.10, EC 2.7.10.1, ErbB-3, erbB3-S, HER3, HER3c-erbB-3, LCCS2, lethal congenital contracture syndrome 2, MDA-BF-1, MGC88033, p180-ErbB3, p45-sErbB3, p85-sErbB3, Proto-oncogene-like protein c-ErbB-3, receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.