Human ErbB3/Her3 Antibody | R&D Systems MAB348-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human ErbB3/Her3 Antibody

catalog :

MAB348-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

66219

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Wu C, Vinton E, PEARSE R, Heo K, Aylward A, Hsieh Y, et al. APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer's pathology in trisomy 21 neurons. Mol Psychiatry. 2022;27:1970-1989 pubmed publisher
Hughes R, Bosanac T, Mao X, Engber T, DiAntonio A, Milbrandt J, et al. Small Molecule SARM1 Inhibitors Recapitulate the SARM1-/- Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate. Cell Rep. 2021;34:108588 pubmed publisher
Stupack J, Xiong X, Jiang L, Zhang T, Zhou L, Campos A, et al. Soluble SORLA Enhances Neurite Outgrowth and Regeneration through Activation of the EGF Receptor/ERK Signaling Axis. J Neurosci. 2020;40:5908-5921 pubmed publisher
Stankova T, Piepkorn L, Bayer T, Jahn O, Tirard M. SUMO1-conjugation is altered during normal aging but not by increased amyloid burden. Aging Cell. 2018;17:e12760 pubmed publisher
Farnoodian M, Sorenson C, Sheibani N. PEDF expression affects the oxidative and inflammatory state of choroidal endothelial cells. Am J Physiol Cell Physiol. 2018;314:C456-C472 pubmed publisher
Maarouf C, Kokjohn T, Whiteside C, Macias M, Kalback W, Sabbagh M, et al. Molecular Differences and Similarities Between Alzheimer's Disease and the 5XFAD Transgenic Mouse Model of Amyloidosis. Biochem Insights. 2013;6:1-10 pubmed publisher
Takasugi N, Sasaki T, Suzuki K, Osawa S, Isshiki H, Hori Y, et al. BACE1 activity is modulated by cell-associated sphingosine-1-phosphate. J Neurosci. 2011;31:6850-7 pubmed publisher
Schulz T, Swistowska A, Liu Y, Swistowski A, Palmarini G, Brimble S, et al. A large-scale proteomic analysis of human embryonic stem cells. BMC Genomics. 2007;8:478 pubmed

product information

master code :

MAB348

SKU :

MAB348-100

product name :

Human ErbB3/Her3 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human ErbB3/Her3 Antibody from R&D Systems is a mouse monoclonal antibody to ErbB3/Her3. This antibody reacts with human. The Human ErbB3/Her3 Antibody has been validated for the following applications: Immunocytochemistry,Immunohistochemistry,Western Blot.

target :

ErbB3/Her3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

66219

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human ErbB3, Ser20-Thr643, Accession # P21860

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human ErbB3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody shows no cross-reactivity with recombinant human (rh) EGF R, rhErbB4, or rhErbB2.

gene symbol :

ERBB3

accessionNumbers :

P21860

applications :

Immunocytochemistry,Immunohistochemistry,Western Blot

USD :

469 USD

alt names :

c-erbB3, EC 2.7.10, EC 2.7.10.1, ErbB-3, erbB3-S, HER3, HER3c-erbB-3, LCCS2, lethal congenital contracture syndrome 2, MDA-BF-1, MGC88033, p180-ErbB3, p45-sErbB3, p85-sErbB3, Proto-oncogene-like protein c-ErbB-3, receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage