Mouse CCR7 Antibody | R&D Systems MAB3477 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse CCR7 Antibody

catalog :

MAB3477

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

4B12

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, blocking or activating experiments

more info or order :

R&D Systems product webpage

citations: 19

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; mouse; ; fig 11c	Mao F, Lv Y, Hao C, Teng Y, Liu Y, Cheng P, et al. Helicobacter pylori-Induced Rev-erbα Fosters Gastric Bacteria Colonization by Impairing Host Innate and Adaptive Defense. Cell Mol Gastroenterol Hepatol. 2021;12:395-425 pubmed publisher
	Artusa P, Nguyen Yamamoto L, Barbier C, Valbon S, Aghazadeh Habashi Y, Djambazian H, et al. Skewed epithelial cell differentiation and premature aging of the thymus in the absence of vitamin D signaling. Sci Adv. 2024;10:eadm9582 pubmed publisher
	Yee Mon K, Kim S, Dai Z, West J, Zhu H, Jain R, et al. Functionalized nanowires for miRNA-mediated therapeutic programming of naïve T cells. Nat Nanotechnol. 2024;19:1190-1202 pubmed publisher
	Wasman Smail S, Ziyad Abdulqadir S, Omar Khudhur Z, Elia Ishaq S, Faqiyazdin Ahmed A, Ghayour M, et al. IL-33 promotes sciatic nerve regeneration in mice by modulating macrophage polarization. Int Immunopharmacol. 2023;123:110711 pubmed publisher
	Liu J, Cheng Y, Zhang X, Chen Y, Zhu H, Chen K, et al. Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity. Cell Rep. 2023;42:111991 pubmed publisher
	Zhang B, Han F, Wang Y, Sun Y, Zhang M, Yu X, et al. Cells-Micropatterning Biomaterials for Immune Activation and Bone Regeneration. Adv Sci (Weinh). 2022;9:e2200670 pubmed publisher
	Del Molino Del Barrio I, Meeson A, Cooke K, Malki M, Barron Millar B, Kirby J, et al. Contribution of Heparan Sulphate Binding in CCL21-Mediated Migration of Breast Cancer Cells. Cancers (Basel). 2021;13: pubmed publisher
	Serrano López J, Hegde S, Kumar S, Serrano J, Fang J, Wellendorf A, et al. Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics. elife. 2021;10: pubmed publisher
	Park E, Myint P, Appiah M, Worawattananutai P, Inprasit J, Prajuabjinda O, et al. Ligand-competent fractalkine receptor is expressed on exosomes. Biochem Biophys Rep. 2021;26:100932 pubmed publisher
	Spenlé C, Loustau T, Murdamoothoo D, Erne W, Beghelli de la Forest Divonne S, Veber R, et al. Tenascin-C Orchestrates an Immune-Suppressive Tumor Microenvironment in Oral Squamous Cell Carcinoma. Cancer Immunol Res. 2020;8:1122-1138 pubmed publisher
	Mansouri S, Katikaneni D, Gogoi H, Pipkin M, Machuca T, Emtiazjoo A, et al. Lung IFNAR1hi TNFR2+ cDC2 promotes lung regulatory T cells induction and maintains lung mucosal tolerance at steady state. Mucosal Immunol. 2020;13:595-608 pubmed publisher
	Mcheik S, Van Eeckhout N, De Poorter C, Gal xe9 s C, Parmentier M, Springael J. Coexpression of CCR7 and CXCR4 During B Cell Development Controls CXCR4 Responsiveness and Bone Marrow Homing. Front Immunol. 2019;10:2970 pubmed publisher
	Chen S, Ge L, Wang H, Cheng Y, Gorantla S, Poluektova L, et al. Eluted 25-hydroxyvitamin D3 from radially aligned nanofiber scaffolds enhances cathelicidin production while reducing inflammatory response in human immune system-engrafted mice. Acta Biomater. 2019;97:187-199 pubmed publisher
	Pei G, Yao Y, Yang Q, Wang M, Wang Y, Wu J, et al. Lymphangiogenesis in kidney and lymph node mediates renal inflammation and fibrosis. Sci Adv. 2019;5:eaaw5075 pubmed publisher
	Pang M, Georgoudaki A, Lambut L, Johansson J, Tabor V, Hagikura K, et al. TGF-Î²1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis. Oncogene. 2016;35:748-60 pubmed publisher
	Dong G, Wang Y, Xiao W, Pacios Pujado S, Xu F, Tian C, et al. FOXO1 regulates dendritic cell activity through ICAM-1 and CCR7. J Immunol. 2015;194:3745-55 pubmed publisher
	Ibrahim M, Barnes J, Osorio E, Anstead G, Jimenez F, Osterholzer J, et al. Deficiency of lymph node-resident dendritic cells (DCs) and dysregulation of DC chemoattractants in a malnourished mouse model of Leishmania donovani infection. Infect Immun. 2014;82:3098-112 pubmed publisher
	Irino T, Takeuchi H, Matsuda S, Saikawa Y, Kawakubo H, Wada N, et al. CC-Chemokine receptor CCR7: a key molecule for lymph node metastasis in esophageal squamous cell carcinoma. BMC Cancer. 2014;14:291 pubmed publisher
	Wan S, Zhou Z, Duan B, Morel L. Direct B cell stimulation by dendritic cells in a mouse model of lupus. Arthritis Rheum. 2008;58:1741-50 pubmed publisher

product information

master code :

MAB3477

SKU :

MAB3477

product name :

Mouse CCR7 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse CCR7 Antibody from R&D Systems is a rat monoclonal antibody to CCR7. This antibody reacts with human,mouse,transgenic mouse. The Mouse CCR7 Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry,Neutralization,ELISA Development,Immunohistochemistry,In vivo assay,CyTOF-reported.

target :

CCR7

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

4B12

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

RBC-2H3 cells expressing mouse CCR7, Accession # NP_031745

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Transgenic Mouse

specificity :

Detects mouse CCR7.

gene symbol :

CCR7

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

CCR7 antibody in Mouse Splenocytes by Immunocytochemistry (ICC).

accessionNumbers :

NP_031745

applications :

Neutralization,Flow Cytometry,ELISA Development,Immunohistochemistry,In vivo assay,Immunocytochemistry,CyTOF-reported

USD :

509 USD

alt names :

BLR2, BLR2C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR7, CCR-7, CD197, CD197 antigen, CDw197, CDw197CC chemokine receptor 7, chemokine (C-C motif) receptor 7, CMKBR7, CMKBR7chemokine (C-C) receptor 7, EBI1, EBI1EBV-induced G protein-coupled receptor 1, EBV-induced G-protein coupled receptor 1, Epstein-Barr virus induced gene 1, Epstein-Barr virus induced G-protein coupled receptor, Epstein-Barr virus-induced G-protein coupled receptor 1, EVI1, lymphocyte-specific G protein-coupled peptide receptor, MIP-3 beta receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage