Human/Mouse/Rat/Hamster ACE-2 Antibody | R&D Systems MAB3437 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat/Hamster ACE-2 Antibody

catalog :

MAB3437

quantity :

100 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

460502

reactivity :

Syrian golden hamster

application :

western blot

more info or order :

R&D Systems product webpage

citations: 7

Reference
Brown J, Sanidad K, Lucotti S, Lieber C, Cox R, Ananthanarayanan A, et al. Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection. Gut Microbes. 2022;14:2105609 pubmed publisher
Rathnasinghe R, Jangra S, Ye C, Cupic A, Singh G, Mart xed nez Romero C, et al. Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera. Nat Commun. 2022;13:3921 pubmed publisher
Winkler E, Chen R, Alam F, Yildiz S, Case J, Uccellini M, et al. SARS-CoV-2 Causes Lung Infection without Severe Disease in Human ACE2 Knock-In Mice. J Virol. 2022;96:e0151121 pubmed publisher
Klouda T, Hao Y, Kim H, Kim J, Olejnik J, Hume A, et al. Interferon-alpha or -beta facilitates SARS-CoV-2 pulmonary vascular infection by inducing ACE2. Angiogenesis. 2021;: pubmed publisher
Rathnasinghe R, Jangra S, Cupic A, Mart xed nez Romero C, Mulder L, Kehrer T, et al. The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera. medRxiv. 2021;: pubmed publisher
Inde Z, Yapp C, Joshi G, Spetz J, Fraser C, Deskin B, et al. Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity. bioRxiv. 2020;: pubmed publisher
Zou Z, Yan Y, Shu Y, Gao R, Sun Y, Li X, et al. Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections. Nat Commun. 2014;5:3594 pubmed publisher

product information

master code :

MAB3437

SKU :

MAB3437

product name :

Human/Mouse/Rat/Hamster ACE-2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat/Hamster ACE-2 Antibody from R&D Systems is a rat monoclonal antibody to ACE-2. This antibody reacts with hamster,human,mouse,primate - cercopithecus aethiops (african green monkey),rat,transgenic mouse. The Human/Mouse/Rat/Hamster ACE-2 Antibody has been validated for the following applications: Western Blot.

target :

ACE-2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

460502

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant mouse ACE-2, Gln18-Thr740 (predicted), Accession # Q8R0I0

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Hamster,Human,Mouse,Primate - Cercopithecus aethiops (African Green Monkey),Rat,Transgenic Mouse

specificity :

Detects mouse ACE-2 in direct ELISAs and human, mouse, rat and hamster ACE-2 in Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse ACE-1 is observed.

gene symbol :

ACE2

accessionNumbers :

Q8R0I0

applications :

Western Blot

USD :

439 USD

alt names :

ACE2, ACEH, ACEHangiotensin I converting enzyme 2, ACE-related carboxypeptidase, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, DKFZp434A014, EC 3.4.17, EC 3.4.17.23, Metalloprotease MPROT15

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage