Human/Mouse/Rat Activin A beta A subunit Antibody | R&D Systems MAB3381 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat Activin A beta A subunit Antibody

catalog :

MAB3381

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

69403

reactivity :

human, mouse, rat

application :

neutralization, blocking or activating experiments

citations: 10

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; 100 ng/ml; loading ...; fig 4d	Nieto C, Bragado R, Municio C, Sierra Filardi E, Alonso B, Escribese M, et al. The Activin A-Peroxisome Proliferator-Activated Receptor Gamma Axis Contributes to the Transcriptome of GM-CSF-Conditioned Human Macrophages. Front Immunol. 2018;9:31 pubmed publisher
	Locci M, Wu J, Arumemi F, Mikulski Z, Dahlberg C, Miller A, et al. Activin A programs the differentiation of human TFH cells. Nat Immunol. 2016;17:976-84 pubmed publisher
	Bufalino A, Cervigne N, de Oliveira C, Fonseca F, Rodrigues P, Macedo C, et al. Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis. PLoS ONE. 2015;10:e0136599 pubmed publisher
	Merfeld Clauss S, Lupov I, Lu H, March K, Traktuev D. Adipose Stromal Cell Contact with Endothelial Cells Results in Loss of Complementary Vasculogenic Activity Mediated by Induction of Activin A. Stem Cells. 2015;33:3039-51 pubmed publisher
	Sierra Filardi E, Puig Kröger A, Blanco F, Nieto C, Bragado R, Palomero M, et al. Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers. Blood. 2011;117:5092-101 pubmed publisher
	Alexander S, Watt F, Sawaji Y, Hermansson M, Saklatvala J. Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB. Arthritis Rheum. 2007;56:3715-25 pubmed
	Kupershmidt L, Amit T, Bar Am O, Youdim M, Blumenfeld Z. The neuroprotective effect of Activin A and B: implication for neurodegenerative diseases. J Neurochem. 2007;103:962-71 pubmed
	Greber B, Lehrach H, Adjaye J. Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal. Stem Cells. 2007;25:455-64 pubmed
	Funaba M, Nakaya K, Ikeda T, Murakami M, Tsuchida K, Sugino H. Requirement of Smad3 for mast cell growth. Cell Immunol. 2006;240:47-52 pubmed
	Yoshinaga K, Inoue H, Utsunomiya T, Sonoda H, Masuda T, Mimori K, et al. N-cadherin is regulated by activin A and associated with tumor aggressiveness in esophageal carcinoma. Clin Cancer Res. 2004;10:5702-7 pubmed

product information

brand :

R&D Systems

master code :

MAB3381

SKU :

MAB3381-100

product name :

Human/Mouse/Rat Activin A beta A subunit Antibody

description :

The Human/Mouse/Rat Activin A beta A subunit Antibody from R&D Systems is a mouse monoclonal antibody to Activin A. This antibody reacts with human, mouse, rat. The Human/Mouse/Rat Activin A beta A subunit Antibody has been validated for the following applications: Neutralization, ELISA Capture (Matched Antibody Pair).

target :

Activin A

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

69403

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human Activin A

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human, Mouse, Rat

specificity :

Detects recombinant human Activin A in ELISAs. Also recognizes Activin A precursor. The amino acid sequences of mature beta A subunits from human, mouse and rat are identical. Therefore, this antibody will also detect the mature beta A subunit from mouse and rat.

gene symbol :

INHBA

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB3381

applications :

Neutralization, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

359 USD

alt names :

activin AB alpha polypeptide, Activin beta-A chain, erythroid differentiation factor, Erythroid differentiation protein, follicle-stimulating hormone-releasing protein, FSH-releasing protein, inhibin beta A chain, inhibin beta A subunit, Inhibin, beta-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.