This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human CCL22/MDC Antibody
catalog :
MAB336
quantity :
100 ug (also 25 ug, 500 ug)
price :
359 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
57226
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, neutralization, immunohistochemistry - paraffin section
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 1e, 2c
Li Z, Wang H, Zeng Q, Yan J, Hu Y, Li H, et al. p65/miR-23a/CCL22 axis regulated regulatory T cells recruitment in hepatitis B virus positive hepatocellular carcinoma. Cancer Med. 2020;9:711-723 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 5a
  • immunocytochemistry; human; loading ...; fig 5d
Ren G, Whittaker J, Leonard C, De Rantere D, Pang D, Salo P, et al. CCL22 is a biomarker of cartilage injury and plays a functional role in chondrocyte apoptosis. Cytokine. 2019;115:32-44 pubmed publisher
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
Mizukami Y, Kono K, Kawaguchi Y, Akaike H, Kamimura K, Sugai H, et al. CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer. Int J Cancer. 2008;122:2286-93 pubmed publisher
Haas J, Schopp L, Storch Hagenlocher B, Fritzsching B, Jacobi C, Milkova L, et al. Specific recruitment of regulatory T cells into the CSF in lymphomatous and carcinomatous meningitis. Blood. 2008;111:761-6 pubmed
Liu L, Bates M, Jarjour N, Busse W, Bertics P, Kelly E. Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha. J Immunol. 2007;179:4840-8 pubmed
Curiel T, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med. 2004;10:942-9 pubmed
Liu L, Jarjour N, Busse W, Kelly E. Enhanced generation of helper T type 1 and 2 chemokines in allergen-induced asthma. Am J Respir Crit Care Med. 2004;169:1118-24 pubmed
Conroy D, Jopling L, Lloyd C, Hodge M, Andrew D, Williams T, et al. CCR4 blockade does not inhibit allergic airways inflammation. J Leukoc Biol. 2003;74:558-63 pubmed
product information
brand :
R&D Systems
master code :
MAB336
SKU :
MAB336-100
product name :
Human CCL22/MDC Antibody
description :
The Human CCL22/MDC Antibody from R&D Systems is a mouse monoclonal antibody to CCL22/MDC. This antibody reacts with human. The Human CCL22/MDC Antibody has been validated for the following applications: Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair).
target :
CCL22/MDC
category :
Primary Antibodies
unit size :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
57226
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human CCL22/MDC, Gly25-Gln93, Accession # O00626.1
isotype :
IgG2b
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human CCL22/MDC in ELISAs and Western blots. In ELISAs, no cross-reactivity with recombinant mouse CCL17, recombinant human (rh) CCL17, or rhCCL21 is observed.
gene symbol :
CCL22
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB336
accessionNumbers :
O00626.1
applications :
Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)
2020 USD :
339
2021 USD :
359 USD
alt names :
A-152E5.1, ABCD-1, CC chemokine STCP-1, C-C motif chemokine 22, chemokine (C-C motif) ligand 22, DC/B-CK, Macrophage-derived chemokine, MDC, MDCStimulated T-cell chemotactic protein 1, MGC34554, SCYA22MDC(1-69), small inducible cytokine A22, small inducible cytokine subfamily A (Cys-Cys), member 22, Small-inducible cytokine A22, STCP-1, stimulated T cell chemotactic protein 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.