Human CCL22/MDC Antibody | R&D Systems MAB336-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCL22/MDC Antibody

catalog :

MAB336-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

57226

reactivity :

human

application :

western blot, ELISA, neutralization, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 15

Reference
Maroui M, Odongo G, Mundo L, Manara F, Mure F, Fusil F, et al. Aflatoxin B1 and Epstein-Barr virus-induced CCL22 expression stimulates B cell infection. Proc Natl Acad Sci U S A. 2024;121:e2314426121 pubmed publisher
Kötting C, Hofmann L, Lotfi R, Engelhardt D, Laban S, Schuler P, et al. Immune-Stimulatory Effects of Curcumin on the Tumor Microenvironment in Head and Neck Squamous Cell Carcinoma. Cancers (Basel). 2021;13: pubmed publisher
Zhao X, Liu S, Chen X, Zhao J, Li F, Zhao Q, et al. L1CAM overexpression promotes tumor progression through recruitment of regulatory T cells in esophageal carcinoma. Cancer Biol Med. 2021;18:547-61 pubmed publisher
Li Z, Wang H, Zeng Q, Yan J, Hu Y, Li H, et al. p65/miR-23a/CCL22 axis regulated regulatory T cells recruitment in hepatitis B virus positive hepatocellular carcinoma. Cancer Med. 2020;9:711-723 pubmed publisher
Antonia A, Gibbs K, Trahair E, Pittman K, Martin A, Schott B, et al. Pathogen Evasion of Chemokine Response Through Suppression of CXCL10. Front Cell Infect Microbiol. 2019;9:280 pubmed publisher
Ren G, Whittaker J, Leonard C, De Rantere D, Pang D, Salo P, et al. CCL22 is a biomarker of cartilage injury and plays a functional role in chondrocyte apoptosis. Cytokine. 2019;115:32-44 pubmed publisher
Yang X, Jiang H, Lei R, Lu W, Tan S, Qin S. Recruitment and significance of Th22 cells and Th17 cells in malignant ascites. Oncol Lett. 2018;16:5389-5397 pubmed publisher
Omland S, Wettergren E, Mollerup S, Asplund M, Mourier T, Hansen A, et al. Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin. BMC Cancer. 2017;17:675 pubmed publisher
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
Mizukami Y, Kono K, Kawaguchi Y, Akaike H, Kamimura K, Sugai H, et al. CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer. Int J Cancer. 2008;122:2286-93 pubmed publisher
Haas J, Schopp L, Storch Hagenlocher B, Fritzsching B, Jacobi C, Milkova L, et al. Specific recruitment of regulatory T cells into the CSF in lymphomatous and carcinomatous meningitis. Blood. 2008;111:761-6 pubmed
Liu L, Bates M, Jarjour N, Busse W, Bertics P, Kelly E. Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha. J Immunol. 2007;179:4840-8 pubmed
Curiel T, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med. 2004;10:942-9 pubmed
Liu L, Jarjour N, Busse W, Kelly E. Enhanced generation of helper T type 1 and 2 chemokines in allergen-induced asthma. Am J Respir Crit Care Med. 2004;169:1118-24 pubmed
Conroy D, Jopling L, Lloyd C, Hodge M, Andrew D, Williams T, et al. CCR4 blockade does not inhibit allergic airways inflammation. J Leukoc Biol. 2003;74:558-63 pubmed

product information

master code :

MAB336

SKU :

MAB336-100

product name :

Human CCL22/MDC Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human CCL22/MDC Antibody from R&D Systems is a mouse monoclonal antibody to CCL22/MDC. This antibody reacts with guinea pig,human,transgenic mouse,xenograft. The Human CCL22/MDC Antibody has been validated for the following applications: Neutralization,Western Blot,ELISA Development,Flow Cytometry,ELISA Capture,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair).

target :

CCL22/MDC

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

57226

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CCL22/MDC, Gly25-Gln93, Accession # O00626.1

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Guinea Pig,Human,Transgenic Mouse,Xenograft

specificity :

Detects human CCL22/MDC in ELISAs and Western blots. In ELISAs, no cross-reactivity with recombinant mouse CCL17, recombinant human (rh) CCL17, or rhCCL21 is observed.

gene symbol :

CCL22

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Chemotaxis Induced by CCL22/MDC and Neutralization by Human CCL22/MDC Antibody.

accessionNumbers :

O00626.1

applications :

Western Blot,Neutralization,ELISA Development,Flow Cytometry,ELISA Capture,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair)

USD :

469 USD

alt names :

A-152E5.1, ABCD-1, CC chemokine STCP-1, C-C motif chemokine 22, chemokine (C-C motif) ligand 22, DC/B-CK, Macrophage-derived chemokine, MDC, MDCStimulated T-cell chemotactic protein 1, MGC34554, SCYA22MDC(1-69), small inducible cytokine A22, small inducible cytokine subfamily A (Cys-Cys), member 22, Small-inducible cytokine A22, STCP-1, stimulated T cell chemotactic protein 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage