This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human CD117/c-kit Antibody
catalog :
MAB332
quantity :
100 ug (also 25 ug, 500 ug)
price :
359 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
47233
reactivity :
human
application :
western blot, ELISA, neutralization, flow cytometry
citations: 4
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s3
Stamm H, Klingler F, Grossjohann E, Muschhammer J, Vettorazzi E, Heuser M, et al. Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option. Oncogene. 2018;37:5269-5280 pubmed publisher
Wang H, Boussouar A, Mazelin L, Tauszig Delamasure S, Sun Y, Goldschneider D, et al. The Proto-oncogene c-Kit Inhibits Tumor Growth by Behaving as a Dependence Receptor. Mol Cell. 2018;72:413-425.e5 pubmed publisher
Pan J, Quintas Cardama A, Kantarjian H, Akin C, Manshouri T, Lamb P, et al. EXEL-0862, a novel tyrosine kinase inhibitor, induces apoptosis in vitro and ex vivo in human mast cells expressing the KIT D816V mutation. Blood. 2007;109:315-22 pubmed
Ameredes B, Calhoun W. Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle. J Allergy Clin Immunol. 2005;116:65-72 pubmed
product information
brand :
R&D Systems
master code :
MAB332
SKU :
MAB332-100
product name :
Human CD117/c-kit Antibody
description :
The Human CD117/c-kit Antibody from R&D Systems is a mouse monoclonal antibody to CD117/c-kit. This antibody reacts with human. The Human CD117/c-kit Antibody has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, Neutralization, CyTOF-ready, ELISA Capture (Matched Antibody Pair).
target :
CD117/c-kit
category :
Primary Antibodies
unit size :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
47233
conjugate :
Unconjugated
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human CD117/c-kit, Gln26-Thr520, Accession # P10721
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human CD117/c-kit in ELISAs and Western blots. In sandwich immunoassays and Western blots, no cross-reactivity with recombinant mouse CD117 is observed.
gene symbol :
KIT
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB332
accessionNumbers :
P10721
applications :
Western Blot, Simple Western, Flow Cytometry, Neutralization, CyTOF-ready, ELISA Capture (Matched Antibody Pair)
2020 USD :
339
2021 USD :
359 USD
alt names :
CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, KIT, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCF R, SCFR, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.